Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | CDC42 | P60953 | 1/20 | 0.34 |
| ▸ | RAC1 | P63000 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6783979 | 0.80 | APP (0.45) | APPPTGS2TDP1KDM4EMAPT | |
| SCHEMBL4143696 | 0.78 | ELANE (0.64) | THRBELANE | |
| SCHEMBL26943657 | 0.77 | THRB (0.54) | THRBPTGS2ELANEMAPTHPGD | |
| SCHEMBL4596363 | 0.77 | THRB (0.54) | THRBELANEKDM4EMAPTHPGD | |
| SCHEMBL5215244 | 0.76 | APP (0.49) | APPTDP1AKR1C3AKR1C2 | |
| SCHEMBL8850119 | 0.76 | APP (0.49) | APPGAAMAPT | |
| SCHEMBL2065202 | 0.75 | TYR (0.48) | APPKDM4EAKR1C3AKR1C2 | |
| SCHEMBL4151935 | 0.75 | ELANE (0.51) | THRBELANEL3MBTL1TDP1MAPT | |
| SCHEMBL18966025 | 0.75 | THRB (0.40) | THRBPTGS2L3MBTL1TDP1 | |
| SCHEMBL1825479 | 0.75 | CXCR2 (0.47) | APPPTGS2ELANEL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130419-A1 | FOAM SHEET AND PRODUCTION PROCESS THEREOF | OJI PAPER CO., LTD (JP) | 2009-05-21 | — | — | US | disclosed |