TOMM34

Mitochondrial import receptor subunit TOM34 · Q15785 · TOMM34 on Sugi Atlas →

149 patent compounds predicted against TOMM34, 119 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL8288590 SCHEMBL8288590 0.76 1/20
SCHEMBL7003055 SCHEMBL7003055 0.74 1/20
SCHEMBL7002920 SCHEMBL7002920 0.70 1/20
SCHEMBL11324603 SCHEMBL11324603 0.66 1/20
SCHEMBL26293177 SCHEMBL26293177 0.64 1/20
SCHEMBL26294993 SCHEMBL26294993 0.63 1/20
SCHEMBL7003174 SCHEMBL7003174 0.62 1/20
SCHEMBL8277600 SCHEMBL8277600 0.62 1/20
SCHEMBL13856578 SCHEMBL13856578 0.62 1/20
SCHEMBL18180597 SCHEMBL18180597 0.62 1/20
SCHEMBL13856429 SCHEMBL13856429 0.61 1/20
SCHEMBL11332843 SCHEMBL11332843 0.60 1/20
SCHEMBL17817446 SCHEMBL17817446 0.60 1/20
SCHEMBL1895132 SCHEMBL1895132 0.60 1/20
SCHEMBL13856422 SCHEMBL13856422 0.60 1/20
SCHEMBL26293182 SCHEMBL26293182 0.59 1/20
SCHEMBL26293211 SCHEMBL26293211 0.58 1/20
SCHEMBL4091316 SCHEMBL4091316 0.57 1/20
SCHEMBL20831148 SCHEMBL20831148 0.57 1/20
SCHEMBL26293025 SCHEMBL26293025 0.57 1/20

Clinical trials — most relevant to TOMM34 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Impact if Desflurane Preconditioning on the Content of the Phospho-GSK-3b in the Rat's Neurons in the Model of I/R PHASE4WITHDRAWN
Cardioprotective Effects of Melatonin in Patients With Cardiomyopathy PHASE3RECRUITING
GM604 Phase 2A Randomized Double-blind Placebo Controlled Pilot Trial in Amyotrophic Lateral Disease (ALS) PHASE2COMPLETED
Biologic Correlative Taxotere/AC PHASE2COMPLETED
Effectiveness of a Brain-Computer Interface Based System for Cognitive Enhancement in the Normal Elderly PHASE1COMPLETED
S-Equol in Alzheimer's Disease (SEAD) Trial PHASE1COMPLETED
Dynamics of Muscle Mitochondria in Type 2 Diabetes (DYNAMMO T2D) EARLY_PHASE1COMPLETED
Natural History Study of SLC25A46 Mutation-related Mitochondriopathy nanCOMPLETED
Mitigating Mitochondrial RNA Release During Aging to Control Inflammation and Senescence nanNOT_YET_RECRUITING
Measuring Protein Turnover in Humans Across the Lifespan by Metabolic Labeling With Deuterium Oxide nanRECRUITING
MERC Proteins in Saliva and GCF in Periodontal Disease (ELISA Study) nanCOMPLETED
Role of Sorcin and Annexin A3 in Breast Cancer Patients nanUNKNOWN
Dynamics of Muscle Mitochondria in Type 2 Diabetes Exercise nanCOMPLETED
sCD163 in ALS Patients nanCOMPLETED
Tissue Sample Study for Mitochondrial Disorders nanENROLLING_BY_INVITATION
Polycystic Ovary Syndrome in Type 1 Diabetes nanNOT_YET_RECRUITING
Transcranial Photobiomodulation for the Treatment of Pediatric Depression nanWITHDRAWN
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular Powerhouse) Dysfunction nanCOMPLETED
Exercise-mediated Rescue of Mitochondrial Dysfunctions Driving Insulin Resistance nanCOMPLETED
Calf Muscle Strength in Mitochondrial Diseases nanCOMPLETED
Effect of Subtle Energy Transmission and Tao Calligraphy Mindfulness Practice on Mitochondrial DNA in Peripheral Blood Leukocytes nanNOT_YET_RECRUITING
GDF-15 as a Biomarker for Mitochondrial Disease nanCOMPLETED
Effect of Branched Chain Amino Acids on Muscle nanCOMPLETED
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS nanRECRUITING
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip nanCOMPLETED
Exercise Training Effects on Muscle Function in Adults With Mitochondrial Myopathy nanRECRUITING
The Natural History of Mitochondrial Diseases nanRECRUITING
Clinical Study of Hydroxytyrosol (HT) in Mitochondrial Diseases nanCOMPLETED
MITOMICS : a Multi-OMICS Approach for the Diagnosis of Mitochondrial Diseases nanRECRUITING
Universal Rare Gene Study: A Registry and Natural History Study of Retinal Dystrophies Associated With Rare Disease-Causing Genetic Variants nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a TOMM34 binder may also engage these)

ProteinNameSimilarity
Q3KRD5 1.000 Q3KRD5 →
A4K2V0 1.000 A4K2V0 →
Q9CYG7 1.000 Q9CYG7 →
Q5U2X2 0.990 Q5U2X2 →
F1RBN2 0.987 F1RBN2 →
Q5JNB5 0.986 Q5JNB5 →
Q27968 0.986 Q27968 →
Q91YW3 0.986 Q91YW3 →
Q80ZX8 0.986 Q80ZX8 →
Q5ZI13 0.986 Q5ZI13 →
Q07617 0.986 Q07617 →
Q13217 0.985 Q13217 →
Q9R0T3 0.985 Q9R0T3 →
P27124 0.985 P27124 →
Q68FQ7 0.985 Q68FQ7 →
Q9M2V1 0.984 Q9M2V1 →
Q20683 0.984 Q20683 →
P30416 0.984 P30416 →
Q9TRY0 0.983 Q9TRY0 →
Q5RF88 0.983 Q5RF88 →
A0A0P0VG31 0.983 A0A0P0VG31 →
Q5U2T9 0.982 Q5U2T9 →
Q91Z38 0.982 Q91Z38 →
Q64378 0.982 Q64378 →
Q8SYD0 0.982 Q8SYD0 →
A8XHX1 0.982 A8XHX1 →
Q7XJS0 0.982 Q7XJS0 →
Q3ZBR5 0.982 Q3ZBR5 →
Q6MG81 0.981 Q6MG81 →
Q94C95 0.981 Q94C95 →