Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 12/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 12/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 12/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 12/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4147402 | 0.76 | HSP90AB1 (0.51) | HSP90AB1HSP90AA1PDK1PDK2PDK3 | |
| SCHEMBL4161521 | 0.71 | PARP10 (0.49) | HSP90AB1HSP90AA1PDK1PDK2PDK3 | |
| SCHEMBL4159615 | 0.70 | HSP90AA1 (0.55) | HSP90AB1HSP90AA1PDK1PDK2PDK3 | |
| SCHEMBL4151865 | 0.69 | HTR2A (0.46) | HSP90AB1HSP90AA1PDK1PDK2PDK3 | |
| SCHEMBL4146730 | 0.69 | MAP3K12 (0.44) | HSP90AB1HSP90AA1 | |
| SCHEMBL4159603 | 0.67 | HSP90AA1 (0.63) | HSP90AB1HSP90AA1PDK1PDK2PDK3 | |
| SCHEMBL4158737 | 0.67 | RAB9A (0.56) | HSP90AB1HSP90AA1PDK1PDK2PDK3 | |
| SCHEMBL3792423 | 0.67 | HSP90AA1 (0.51) | HSP90AB1HSP90AA1PDK1PDK2PDK3 | |
| SCHEMBL4143175 | 0.66 | HSP90AA1 (0.62) | HSP90AB1HSP90AA1 | |
| SCHEMBL4155308 | 0.66 | HSP90AA1 (0.61) | HSP90AB1HSP90AA1PDK1PDK2PDK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | claimed |
| EP-1879863-A1 | AMIDE RESORCINOL COMPOUNDS | Pfizer, Inc. (US) | 2008-01-23 | — | — | EP | claimed |
| WO-2006117669-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER INC. (US) | 2006-11-09 | — | — | WO | claimed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| EP-1879863-A1 | AMIDE RESORCINOL COMPOUNDS | Pfizer, Inc. (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117669-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER INC. (US) | 2006-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | HSP90AB1, HSP90AA1, HSP90AB2P | SCN3A 2404/4885HSP90AB1 1/4885HSP90AA1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.