Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | CTSS | P25774 | 13/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4286100 | 0.92 | CTSK (0.49) | CTSKCTSSCTSLCTSCKDM4E | |
| SCHEMBL4133131 | 0.88 | CTSK (0.59) | CTSKCTSSCTSLCTSCKDM4E | |
| SCHEMBL4151316 | 0.88 | CTSK (0.47) | CTSKCTSSCTSLCTSCKDM4E | |
| SCHEMBL4137299 | 0.87 | CTSK (0.53) | CTSKCTSSCTSLCTSCKDM4E | |
| SCHEMBL5763472 | 0.87 | CTSK (0.65) | CTSKCTSSCTSL | |
| SCHEMBL4141258 | 0.82 | CTSS (0.53) | CTSKCTSSCTSLCTSCDRD2 | |
| SCHEMBL4137153 | 0.82 | CTSK (0.46) | CTSKCTSSKDM4ETSHRHTR1A | |
| SCHEMBL4137151 | 0.80 | CTSS (0.57) | CTSKCTSSCTSL | |
| SCHEMBL13924780 | 0.79 | CTSK (0.61) | CTSKCTSSCTSLCTSCTSHR | |
| SCHEMBL4131486 | 0.79 | POLB (0.41) | CTSKKDM4ETSHRMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054467-A1 | Pyrrolo Pyrimidines as Agents for the Inhibition of Cystein Proteases | BETSCHART CLAUDIA | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054467-A1 | Pyrrolo Pyrimidines as Agents for the Inhibition of Cystein Proteases | CTSK, CTSS, CTSZ | CTSK 1/4885CTSS 2/4885CTSL 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.