Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 8/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYBB | P04839 | 2/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | HBB | P68871 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2604882 | 0.84 | RELA (0.58) | NOX1APPL3MBTL1CYBBNOX4 | |
| SCHEMBL2604929 | 0.81 | NPC1 (0.61) | NOX1APPL3MBTL1CYBBNOX4 | |
| SCHEMBL14328196 | 0.81 | NOX1 (0.42) | NOX1APPL3MBTL1CYBBNOX4 | |
| SCHEMBL14329681 | 0.79 | NOX1 (0.43) | NOX1APPL3MBTL1CYBBNOX4 | |
| SCHEMBL13840827 | 0.79 | NOX1 (0.46) | NOX1APPL3MBTL1CYBBNOX4 | |
| Iodide SCHEMBL7032875 | 0.79 | MEN1 (0.63) | NOX1APPMEN1KMT2ANPC1 | |
| SCHEMBL4142559 | 0.79 | MEN1 (0.46) | NOX1APPL3MBTL1CYBBNOX4 | |
| Iodide SCHEMBL7032870 | 0.79 | MEN1 (0.63) | NOX1APPMEN1KMT2ANPC1 | |
| SCHEMBL12806229 | 0.78 | ALDH1A1 (0.44) | NOX1APPRELAKMT2AALDH1A1 | |
| SCHEMBL12733254 | 0.78 | ALDH1A1 (0.44) | KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090035576-A1 | Nanoparticles for two-photon activated photodynamic therapy and imaging | HEALTH RESEARCH, INC. | 2009-02-05 | — | — | US | disclosed |
| US-20080233051-A1 | Nanoparticles for two-photon activated photodynamic therapy and imaging | HEALTH RESEARCH, INC. | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080233051-A1 | Nanoparticles for two-photon activated photodynamic therapy and imaging | ORMDL3, PPOX, ORC3 | NOX1 370/4885APP 1759/4885L3MBTL1 407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.