Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | SNCA | P37840 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.49 |
| ▸ | VCP | P55072 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2686075 | 0.84 | NFE2L2 (0.65) | NFE2L2CYP19A1SNCAMAPTMAOB | |
| SCHEMBL4403012 | 0.84 | NFE2L2 (0.65) | NFE2L2CYP19A1SNCAMAPTMAOB | |
| SCHEMBL10496489 | 0.84 | NFE2L2 (0.68) | NFE2L2CYP19A1SNCAMAPTMAOB | |
| SCHEMBL13877019 | 0.84 | NFE2L2 (0.68) | NFE2L2CYP19A1SNCAMAPTMAOB | |
| SCHEMBL9798094 | 0.84 | NFE2L2 (0.68) | NFE2L2CYP19A1SNCAMAPTMAOB | |
| SCHEMBL27675542 | 0.81 | NFE2L2 (0.68) | NFE2L2CYP19A1SNCAMAPTALDH1A1 | |
| SCHEMBL13622504 | 0.79 | NFE2L2 (0.79) | NFE2L2CYP19A1MAPTMAOBALDH1A1 | |
| SCHEMBL4143068 | 0.79 | CYP1A2 (0.49) | NFE2L2MAOBALDH1A1LMNAMEN1 | |
| SCHEMBL1405314 | 0.78 | NFE2L2 (1.00) | NFE2L2CYP19A1SNCAMAPTMAOB | |
| SCHEMBL1405312 | 0.78 | NFE2L2 (1.00) | NFE2L2CYP19A1SNCAMAPTMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633312-B2 | Dibenzocycloheptatone derivatives and pharmaceutical agents containing said compounds | C-A-I-R BIOSCIENCES GMBH (DE) | 2014-01-21 | — | — | US | disclosed |
| US-20120115862-A1 | DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | C-A-I-R BIOSCIENCES GMBH (DE) | 2012-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115862-A1 | DIBENZOCYCLOHEPTATONE DERIVATIVES AND PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS | IL1B, NFKBIA, IL1R1 | NFE2L2 311/4885CYP19A1 154/4885SNCA 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.