SCHEMBL4151916

SCHEMBL4151916

C[CH][Si](OCCCC)(OCCCC)OCCCC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
ALDH1A1 P00352 1/20 0.37
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
ATM Q13315 1/20 0.34
TSHR P16473 3/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.32
HCAR2 Q8TDS4 1/20 0.30
LMNA P02545 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4168325 0.83 CA1 (0.31) CA1CA2
SCHEMBL2125839 0.82 ADRB2 (0.36) ADRB2ADRB1ADRB3ALDH1A1CA1
SCHEMBL7049706 0.81 ADRB2 (0.39) ADRB2ADRB1ADRB3ALDH1A1CA1
SCHEMBL4762865 0.80 ADRB2 (0.35) ADRB2ADRB1ADRB3ALDH1A1ATM
SCHEMBL6550142 0.77 ADRB2 (0.36) ADRB2ADRB1ADRB3ALDH1A1CA1
SCHEMBL129087 0.77 TSHR (0.40) ADRB2ADRB1ADRB3ALDH1A1CA1
SCHEMBL20394649 0.75 TSHR (0.39) ADRB2ADRB1ADRB3ALDH1A1ATM
SCHEMBL7764826 0.75 ADRB2 (0.35) ADRB2ADRB1ADRB3ALDH1A1ATM
SCHEMBL17633937 0.75 ALDH1A1 (0.31) ADRB2ADRB1ADRB3ALDH1A1
SCHEMBL17633936 0.75 ALDH1A1 (0.31) ADRB2ADRB1ADRB3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090198028-A1 1,2-dithiol-3-thiones as chain-transfer agents in free-radical polymerization reactions BASF SE (DE) 2009-08-06 US disclosed