Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.50 |
| ▸ | GPX4 | P36969 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | POLQ | O75417 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MLYCD | O95822 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4164220 | 0.91 | ALDH1A1 (0.46) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL4173745 | 0.83 | MLYCD (0.48) | ALDH1A1RAB9ANPC1PAX8TP53 | |
| SCHEMBL4422100 | 0.82 | POLQ (0.53) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL4158995 | 0.82 | MLYCD (0.50) | ALDH1A1HPGDMLYCD | |
| SCHEMBL4163290 | 0.81 | ALDH1A1 (0.61) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL4164807 | 0.79 | ALDH1A1 (0.62) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL4154918 | 0.78 | TP53 (0.64) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL14229492 | 0.78 | ALDH1A1 (0.57) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL14201125 | 0.76 | ALDH1A1 (0.55) | ALDH1A1RAB9ANPC1PAX8GPX4 | |
| SCHEMBL4163047 | 0.74 | CETP (0.40) | ALDH1A1RAB9ANPC1PAX8GPX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | LABORATORIOS SALVAT, S.A. (ES) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | PPARG, PPARD, TYRO3 | ALDH1A1 2505/4885RAB9A 2235/4885NPC1 3120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.