Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4214376 | 0.86 | SCN10A (0.44) | SCN9ASCN2ASCN3ASCN10AKCNH2 | |
| SCHEMBL18699123 | 0.84 | HPGD (0.42) | KMT2AKDM4EMAPTLMNARAB9A | |
| SCHEMBL1828539 | 0.81 | AKR1C4 (0.47) | SCN9ASCN2ASCN3ASCN10AKCNH2 | |
| SCHEMBL14818820 | 0.79 | PLK1 (0.48) | KMT2AKDM4EMAPTLMNARAB9A | |
| SCHEMBL4157657 | 0.77 | DOT1L (0.56) | KMT2AKDM4EMAPTRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL25433125 | 0.77 | PTPRC (0.41) | PTPRCKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL4373698 | 0.77 | KDM4E (0.57) | PTPRCKDM4EMAPTLMNARAB9A | |
| SCHEMBL13527534 | 0.77 | ALDH1A1 (0.41) | PTPRCKMT2AKDM4EMAPTLMNA | |
| SCHEMBL4147701 | 0.77 | LMNA (0.46) | PTPRCKMT2AKDM4EMAPTLMNA | |
| SCHEMBL14195446 | 0.76 | RAF1 (0.42) | KMT2AKDM4EMAPTLMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | BASF SE (DE) | 2009-05-21 | — | — | US | disclosed |
| US-4683330-A | ANTICOAGULANTS, ANTIULCER AGENTS | THE UPJOHN COMPANY (US) | 1987-07-28 | — | — | US | disclosed |
| US-4668814-A | ANTIULCER AGENTS, ANTIASHMATICS, ANTICOAGULANTS | THE UPJOHN COMPANY (US) | 1987-05-26 | — | — | US | disclosed |
| US-4628110-A | Novel 9-substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1986-12-09 | — | — | US | disclosed |
| US-4621100-A | Treatment of osteoporosis with prostaglandins | THE UPJOHN COMPANY (US) | 1986-11-04 | — | — | US | disclosed |
| EP-0089769-B1 | 9-SUBSTITUTED CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-10-01 | — | — | EP | disclosed |
| EP-0092352-B1 | 9-SUBSTITUTED CARBACYCLINS | THE UPJOHN COMPANY (US) | 1986-07-02 | — | — | EP | disclosed |
| EP-0086611-B1 | 9-SUBSTITUTED CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-05-21 | — | — | EP | disclosed |
| US-4590297-A | Novel 9-substituted carbacyclin analogs | THE UPJOHN COMPANY (US) | 1986-05-20 | — | — | US | disclosed |
| EP-0087237-B1 | CARBACYCLIN ANALOGUES | THE UPJOHN COMPANY (US) | 1986-05-14 | — | — | EP | disclosed |
| US-4160095-A | PROSTAGLANDINS; ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1979-07-03 | — | — | US | disclosed |
| US-4157441-A | PROSTAGLANDINS, ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1979-06-05 | — | — | US | disclosed |
| US-4151351-A | PROSTAGLANDINS, ANTIINFLAMMATORY | THE UPJOHN COMPANY (US) | 1979-04-24 | — | — | US | disclosed |
| US-4131738-A | 6-Hydroxy-PGE1 compounds | THE UPJOHN COMPANY (US) | 1978-12-26 | — | — | US | disclosed |
| US-4128713-A | 6,7-Didehydro-PGI1 compounds | THE UPJOHN COMPANY (US) | 1978-12-05 | — | — | US | disclosed |
| US-4126744-A | PROSTACYCLIN, MUSCLE STIMULANTS, PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
| US-4112224-A | PROSTAGLANDIN | THE UPJOHN COMPANY (US) | 1978-09-05 | — | — | US | disclosed |
| US-4109082-A | PROSTACYCLIN ANALOGS; SMOOTH MUSCLE STIMULATORS | THE UPJOHN COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4100192-A | Inter-phenylene-PG amides | THE UPJOHN COMPANY (US) | 1978-07-11 | — | — | US | disclosed |
| US-4097489-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131657-A1 | PROCESS FOR ALKENYLATING CARBOXAMIDES | PRMT5, CYC1, CBR3 | SCN9A 3143/4885SCN2A 1397/4885SCN3A 2747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.