Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.72 |
| ▸ | MAOA | P21397 | 5/20 | 0.72 |
| ▸ | QPCT | Q16769 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.60 |
| ▸ | FLT3 | P36888 | 2/20 | 0.57 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15245959 | 0.87 | FLT3 (0.74) | MAOBMAOAQPCTCYP19A1FLT3 | |
| SCHEMBL8308052 | 0.86 | MAOB (0.67) | MAOBMAOAQPCTCYP19A1FLT3 | |
| SCHEMBL8305728 | 0.85 | MAOB (0.66) | MAOBMAOAQPCTCYP19A1FLT3 | |
| SCHEMBL4056341 | 0.85 | MAPT (0.72) | MAOBMAOACYP19A1NPC1CYP3A4 | |
| SCHEMBL13741293 | 0.84 | L3MBTL1 (0.71) | MAOBMAOANPC1CYP3A4MAPT | |
| SCHEMBL3185003 | 0.84 | MAOB (0.62) | MAOBMAOAQPCTCYP19A1FLT3 | |
| SCHEMBL24882669 | 0.83 | EGFR (0.78) | MAOBMAOACYP19A1FLT3IP6K2 | |
| SCHEMBL14048682 | 0.83 | MAPT (0.78) | MAOBMAOAQPCTCYP19A1FLT3 | |
| SCHEMBL4575435 | 0.83 | CYP1B1 (0.71) | MAOBMAOACYP19A1FLT3IP6K2 | |
| SCHEMBL8304836 | 0.82 | CYP1B1 (0.66) | MAOBMAOACYP19A1FLT3IP6K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710097-B2 | Flavonoid dimers and methods of making and using such | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2014-04-29 | — | — | US | disclosed |
| US-8710097-B2 | Flavonoid dimers and methods of making and using such | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2014-04-29 | — | — | US | disclosed |
| US-20090197943-A1 | Flavonoid Dimers and Methods of Making and Using Such | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2009-08-06 | — | — | US | disclosed |
| US-20090197943-A1 | Flavonoid Dimers and Methods of Making and Using Such | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2009-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197943-A1 | Flavonoid Dimers and Methods of Making and Using Such | ABCB1, ABCC1, SLC47A2 | MAOB 1098/4885MAOA 1871/4885QPCT 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.