SCHEMBL4153705

SCHEMBL4153705

[CH2]COCCOCCOS(C)(=O)=O

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
USP2 O75604 2/20 0.50
TSHR P16473 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALDH1A1 P00352 1/20 0.50
LMNA P02545 1/20 0.50
MMP9 P14780 1/20 0.50
ALOX15 P16050 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1642834 0.98 USP2 (0.52) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL1627440 0.87 USP2 (0.63) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL4149480 0.87 USP2 (0.63) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL29541499 0.87 USP2 (0.63) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL4143916 0.87 USP2 (0.63) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL4140372 0.87 USP2 (0.63) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL4148516 0.87 USP2 (0.63) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL267542 0.87 USP2 (0.63) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL4154180 0.87 USP2 (0.63) USP2TSHRKDM4EALDH1A1LMNA
SCHEMBL3171617 0.87 USP2 (0.63) USP2TSHRKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090170934-A1 MANUFACTURING PROCESS FOR NO-DONATING COMPOUNDS SUCH AS NO-DONATING DICLOFENAC NICOX SA 2009-07-02 US disclosed
US-20090096314-A1 ELECTRIC MOTOR HONDA MOTOR CO., LTD. (JP) 2009-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090170934-A1 MANUFACTURING PROCESS FOR NO-DONATING COMPOUNDS SUCH AS NO-DONATING DICLOFENAC NOS2, NOS1, NOS3 USP2 1318/4885TSHR 4651/4885KDM4E 1339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.