Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 1/20 | 0.62 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.61 |
| ▸ | MMP8 | P22894 | 2/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | CPA1 | P15085 | 1/20 | 0.57 |
| ▸ | CPA2 | P48052 | 1/20 | 0.57 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | F13A1 | P00488 | 1/20 | 0.56 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.56 |
| ▸ | CHRNG | P07510 | 2/20 | 0.56 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.56 |
| ▸ | CHRND | Q07001 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.55 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819246 | 1.00 | CTSS (0.62) | CTSSCTSKGRIA1MMP8MMP2 | |
| SCHEMBL4151677 | 0.95 | GRIA1 (0.66) | CTSSCTSKGRIA1MMP8MMP2 | |
| SCHEMBL13819248 | 0.95 | GRIA1 (0.66) | CTSSCTSKGRIA1MMP8MMP2 | |
| SCHEMBL20865715 | 0.88 | MMP8 (0.55) | CTSSCTSKGRIA1MMP8MMP2 | |
| SCHEMBL21560530 | 0.86 | CHRNA1 (0.73) | CTSSGRIA1MMP8MMP2MMP9 | |
| SCHEMBL21560529 | 0.86 | CHRNA1 (0.73) | CTSSGRIA1MMP8MMP2MMP9 | |
| SCHEMBL18951703 | 0.83 | CTSS (0.59) | CTSSCTSKGRIA1MMP8MMP9 | |
| SCHEMBL15692299 | 0.83 | MME (0.66) | CTSSCTSKCPA1CPA2CPA4 | |
| SCHEMBL5997104 | 0.83 | MME (0.66) | CTSSCTSKCPA1CPA2CPA4 | |
| SCHEMBL15692300 | 0.83 | MME (0.66) | CTSSCTSKCPA1CPA2CPA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1876169-B1 | PHENYL-CONTAINING N-ACYL AMINE AND AMINOACID DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, A PHARMACEUTICAL COMPOSITION AND THE USE THEREOF | OBSCHESTVO S OGRANICHENNOI OTVETSTENNOSTIYU PHARMENTPR (RU) | 2015-12-30 | — | — | EP | claimed |
| US-8309766-B2 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | Obschestvo S. Organichennoi Otvetstvennostiyu Pharmenterprises (RU) | 2012-11-13 | — | — | US | claimed |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2009-04-30 | — | — | US | claimed |
| EP-1876169-A1 | PHENYL-CONTAINING N-ACYL AMINE AND AMINOACID DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, A PHARMACEUTICAL COMPOSITION AND THE USE THEREOF | Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) | 2008-01-09 | — | — | EP | claimed |
| EP-1876169-B1 | PHENYL-CONTAINING N-ACYL AMINE AND AMINOACID DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, A PHARMACEUTICAL COMPOSITION AND THE USE THEREOF | OBSCHESTVO S OGRANICHENNOI OTVETSTENNOSTIYU PHARMENTPR (RU) | 2015-12-30 | — | — | EP | disclosed |
| US-8309766-B2 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | Obschestvo S. Organichennoi Otvetstvennostiyu Pharmenterprises (RU) | 2012-11-13 | — | — | US | disclosed |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | PAH, MAOA, APEH | CTSS 617/4885CTSK 1904/4885GRIA1 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.