Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207129 | 0.83 | MAPT (0.40) | MAPTKDM4EKMT2AMEN1PTGDR2 | |
| SCHEMBL9207313 | 0.83 | MAPT (0.40) | MAPTKDM4EKMT2AMEN1PTGDR2 | |
| SCHEMBL7511256 | 0.81 | MAPT (0.41) | MAPTKDM4EKMT2AMEN1PTGDR2 | |
| SCHEMBL3094958 | 0.81 | HRH4 (0.39) | MAPTKDM4EKMT2AMEN1PTGDR2 | |
| SCHEMBL17251279 | 0.78 | HCRTR1 (0.43) | SCN10AMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL3081865 | 0.77 | HRH4 (0.37) | PTGDR2HRH4CDC7 | |
| SCHEMBL4153902 | 0.76 | SCN10A (0.38) | SCN10AMAPTKDM4EKMT2AMEN1 | |
| SCHEMBL9206473 | 0.74 | CNR1 (0.36) | KDM4ECAMKK2HRH4IDO1CNR1 | |
| SCHEMBL29289787 | 0.74 | MAPT (0.40) | MAPTKDM4EKMT2AMEN1PTGDR2 | |
| SCHEMBL17250826 | 0.74 | IDO1 (0.42) | KDM4EKMT2AMEN1IDO1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082346-A1 | NEW ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS AND USES IN TREATMENTS OF OBESITY AND DIABETES MELLITUS - 087 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |