Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27632867 | 0.83 | GSK3B (0.37) | SCN10AKMT2ATDP1KDM4ESMN1; SMN2 | |
| SCHEMBL3094967 | 0.81 | RET (0.37) | SCN10ACNR2KMT2ATDP1KDM4E | |
| SCHEMBL31214525 | 0.78 | ADORA3 (0.44) | CNR1CNR2TDP1SMN1; SMN2NPC1 | |
| SCHEMBL3081871 | 0.77 | IRAK4 (0.40) | RETOPRM1 | |
| SCHEMBL4153906 | 0.76 | SCN10A (0.40) | SCN10ACNR1CNR2KMT2ATDP1 | |
| SCHEMBL31214487 | 0.75 | ADORA3 (0.44) | TDP1KDM4ESMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL19691288 | 0.75 | HRH4 (0.36) | SCN10AKDM4EGSK3BCDC7LCK | |
| SCHEMBL29210935 | 0.75 | NOS3 (0.41) | SCN10AKMT2ATDP1KDM4ESMN1; SMN2 | |
| SCHEMBL28002669 | 0.72 | SCN10A (0.41) | SCN10AKMT2AKDM4ESMN1; SMN2GSK3B | |
| SCHEMBL4414124 | 0.72 | PARP1 (0.46) | KMT2AKDM4ESMN1; SMN2HTTCDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082346-A1 | NEW ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS AND USES IN TREATMENTS OF OBESITY AND DIABETES MELLITUS - 087 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |