Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207313 | 1.00 | MAPT (0.40) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL9206473 | 0.92 | CNR1 (0.36) | KDM4ECAMKK2GSK3BALOX5APFEN1 | |
| SCHEMBL29289787 | 0.84 | MAPT (0.40) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL4153906 | 0.83 | SCN10A (0.40) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL7511256 | 0.83 | MAPT (0.41) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL3094958 | 0.80 | HRH4 (0.39) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL17503606 | 0.79 | KDM4E (0.43) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL2246378 | 0.78 | KDM4E (0.41) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL30588518 | 0.76 | KDM4E (0.41) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL16741044 | 0.76 | OPRM1 (0.34) | CAMKK2GSK3BALOX5APFEN1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422456-B1 | Pyridine derivatives and their use in combating unwanted plant growth | BASF AG (DE) | 1995-05-03 | — | — | EP | claimed |