Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 5/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.35 |
| ▸ | CAMKK1 | Q8N5S9 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9207129 | 0.83 | MAPT (0.40) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL9207313 | 0.83 | MAPT (0.40) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL4153906 | 0.81 | SCN10A (0.40) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL3094958 | 0.78 | HRH4 (0.39) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL9206473 | 0.77 | CNR1 (0.36) | KDM4ECAMKK2HRH4GSK3BCNR1 | |
| SCHEMBL31668887 | 0.76 | HTT (0.43) | MAPTCAMKK2HRH4GSK3BALOX5AP | |
| SCHEMBL26618870 | 0.75 | IDO1 (0.39) | HRH4CNR1CNR2ALOX5APFEN1 | |
| SCHEMBL3081865 | 0.74 | HRH4 (0.37) | HRH4CDC7PTGDR2 | |
| SCHEMBL29289787 | 0.73 | MAPT (0.40) | MAPTKDM4EKMT2AMEN1CAMKK2 | |
| SCHEMBL20899022 | 0.73 | L3MBTL1 (0.39) | MAPTKDM4EKMT2AMEN1CAMKK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575455-A2 | METHODS AND COMPOSITIONS FOR TREATING A SUBJECT FOR CENTRAL NERVOUS SYSTEM (CNS) INJURY | The Regents of the University of California (US) | 2013-04-10 | — | — | EP | disclosed |
| WO-2011153377-A2 | METHODS AND COMPOSITIONS FOR TREATING A SUBJECT FOR CENTRAL NERVOUS SYSTEM (CNS) INJURY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-08 | — | — | WO | disclosed |