Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.39 |
| ▸ | CD38 | P28907 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014566 | 0.92 | NNMT (0.51) | NNMTKDM4EMEN1KMT2AGABRP | |
| SCHEMBL25149306 | 0.81 | PARP15 (0.42) | NNMTKDM4ECDC7MEN1MAPT | |
| SCHEMBL25148626 | 0.81 | PARP15 (0.42) | NNMTKDM4ECDC7MEN1MAPT | |
| SCHEMBL4598550 | 0.80 | NPC1 (0.51) | KDM4EKMT2A | |
| SCHEMBL29580982 | 0.78 | PARP1 (0.43) | NNMTKDM4ECDC7MEN1MAPT | |
| SCHEMBL21816284 | 0.77 | GABRP (0.53) | KDM4EMEN1MAPTKMT2AGABRP | |
| SCHEMBL21906150 | 0.76 | PARP1 (0.38) | KDM4ECDC7MEN1MAPTKMT2A | |
| SCHEMBL4329258 | 0.74 | MAPT (0.42) | NNMTKDM4ECDC7MEN1MAPT | |
| SCHEMBL17861720 | 0.73 | PIM3 (0.48) | SYK | |
| SCHEMBL22093086 | 0.72 | PARP1 (0.40) | KMT2ASYKEGFRTECBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009082346-A1 | NEW ACETYL COENZYME A CARBOXYLASE (ACC) INHIBITORS AND USES IN TREATMENTS OF OBESITY AND DIABETES MELLITUS - 087 | ASTRAZENECA AB (SE) | 2009-07-02 | — | — | WO | disclosed |