SCHEMBL4153920

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17279666	0.89	ERBB2 (0.48)	ERBB2TDP1L3MBTL1CYP19A1CYP11B2
	SCHEMBL19784873	0.82	CYP19A1 (0.57)	ERBB2CYP19A1CYP11B2ARKMT2A
	SCHEMBL4163879	0.81	HTR6 (0.46)	CYP19A1CYP11B2MAOBCYP11B1NR3C1
	SCHEMBL13802226	0.81	PARP1 (0.50)	CYP19A1CYP11B2MAOBCYP11B1NR3C1
	SCHEMBL6239187	0.81	MIF (0.64)	TDP1CYP19A1CYP11B2MAOBCYP11B1
	SCHEMBL4158887	0.81	MAOB (0.49)	CYP19A1CYP11B2MAOBCYP11B1NR3C1
	SCHEMBL4042552	0.81	AR (0.55)	TDP1L3MBTL1CYP19A1CYP11B2MAOB
	SCHEMBL13508434	0.80	CYP19A1 (0.44)	CYP19A1CYP11B2MAOBCYP11B1NR3C1
	SCHEMBL4157456	0.79	CYP19A1 (0.46)	CYP19A1CYP11B2MAOBCYP11B1NR3C1
	SCHEMBL8548101	0.78	MAOB (0.77)	CYP19A1CYP11B2MAOBMIFKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.