Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4618886 | 0.90 | POLB (0.38) | CHRM1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL4166952 | 0.85 | CCR2 (0.40) | CHRM1LMNAPOLBALDH1A1CCR2 | |
| Trifluoroacetic Acid SCHEMBL4168691 | 0.84 | CHRM2 (0.41) | CHRM1CCR2CHRM2CHRM4 | |
| Trifluoroacetic Acid SCHEMBL4171628 | 0.84 | CCR2 (0.38) | CHRM1LMNAALDH1A1CCR2KMT2A | |
| Trifluoroacetic Acid SCHEMBL4171681 | 0.84 | CCR2 (0.38) | CHRM1CCR2CHRM2CHRM4 | |
| Trifluoroacetic Acid SCHEMBL4171821 | 0.81 | CCR2 (0.38) | CHRM1LMNAALDH1A1CCR2KMT2A | |
| Trifluoroacetic Acid SCHEMBL4618890 | 0.79 | ALDH1A1 (0.35) | CHRM1CYP1A2CYP3A4CYP2C19ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL4622701 | 0.78 | CHRM1 (0.46) | CHRM1NPY5R | |
| SCHEMBL4151885 | 0.78 | KMT2A (0.43) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA | |
| Trifluoroacetic Acid SCHEMBL4154033 | 0.77 | CYP1A2 (0.39) | CYP1A2CYP3A4CYP2C9CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | CHRM1 4291/4885CYP1A2 2863/4885CYP3A4 3542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.