Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Paraquat. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | QDPR | P09417 | 2/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11478149 | 0.89 | PABPC1 (0.63) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| Paraquat SCHEMBL11565178 | 0.86 | SLC6A4 (0.56) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| SCHEMBL9362893 | 0.85 | ALDH1A1 (0.41) | SLC6A4TERTHDAC8 | |
| Paraquat SCHEMBL15224803 | 0.84 | SLC6A4 (0.53) | SLC6A4SLC22A2SLC22A1SLC22A3PABPC1 | |
| SCHEMBL2780056 | 0.80 | HDAC8 (0.41) | SLC6A4HDAC8 | |
| Bromide SCHEMBL4081210 | 0.80 | KMT2A (0.58) | SLC6A4 | |
| Bromide SCHEMBL4078957 | 0.80 | KMT2A (0.58) | SLC6A4 | |
| Bromide SCHEMBL4079380 | 0.80 | KMT2A (0.58) | SLC6A4 | |
| SCHEMBL2652712 | 0.79 | PGR (0.47) | SLC6A4 | |
| SCHEMBL5483989 | 0.79 | HDAC8 (0.64) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4337017-A1 | HERBICIDE/SAFENER COMBINATION BASED ON SAFENERS FROM THE CLASS OF SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACIDS AND THEIR SALTS | Bayer Aktiengesellschaft (DE) | 2024-03-20 | — | — | EP | claimed |
| WO-2022152728-A1 | HERBICIDAL COMPOSITIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-07-21 | — | — | WO | claimed |
| JP-4013603-A | — | — | None | — | — | JP | disclosed |
| JP-54119030-A | — | — | None | — | — | JP | disclosed |
| US-20250270581-A1 | METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE | MONSANTO TECHNOLOGY LLC (US) | 2025-08-28 | — | — | US | disclosed |
| US-20250228243-A1 | METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE | MONSANTO TECHNOLOGY LLC (US) | 2025-07-17 | — | — | US | disclosed |
| US-12325646-B2 | Fertigation water treatment | UNIVERSITY OF GUELPH (CA) | 2025-06-10 | — | — | US | disclosed |
| US-20250024837-A1 | PESTICIDE SYSTEM | BANISH, MICHELE | 2025-01-23 | — | — | US | disclosed |
| EP-4378314-A2 | HERBICIDAL COMPOSITIONS | Bayer AG (DE) | 2024-06-05 | — | — | EP | disclosed |
| CN-114340393-B | Herbicidal composition | 拜耳公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-4337017-A1 | HERBICIDE/SAFENER COMBINATION BASED ON SAFENERS FROM THE CLASS OF SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACIDS AND THEIR SALTS | Bayer Aktiengesellschaft (DE) | 2024-03-20 | — | — | EP | disclosed |
| US-20100234226-A1 | HERBICIDE COMBINATION COMPRISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2010-09-16 | — | — | US | disclosed |
| US-7500895-B2 | Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device | SEIKO EPSON CORPORATION (JP) | 2009-03-10 | — | — | US | disclosed |
| US-20060276339-A1 | Methods and compositions for increasing the efficacy of biologically-active ingredients | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2006-12-07 | — | — | US | disclosed |
| US-20060127563-A1 | Patterned substrate, electro-optical device, and method for manufacturing an electro-optical device | SEIKO EPSON CORPORATION (JP) | 2006-06-15 | — | — | US | disclosed |
| US-20050287392-A1 | Organic electroluminescent device, method for producing the same, and electronic apparatus | SEIKO EPSON CORPORATION (JP) | 2005-12-29 | — | — | US | disclosed |
| JP-H0413603-A | HERBICIDAL COMPOSITION | IMPERIAL CHEM IND PLC <ICI> | 1992-01-17 | — | — | JP | disclosed |
| EP-0276911-A2 | Method of formulating herbicidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-03 | — | — | EP | disclosed |
| JP-S54119030-A | HERBICIDAL COMPOSITION | OTSUKA CHEM CO LTD | 1979-09-14 | — | — | JP | disclosed |
| JP-H00413603-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276339-A1 | Methods and compositions for increasing the efficacy of biologically-active ingredients | ENPP1, ENPP3, SMPD1 | SLC6A4 4266/4885SLC22A2 3918/4885SLC22A1 3692/4885 |
| US-20250270581-A1 | METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE | PPOX, PTPRG, PAOX | SLC6A4 1319/4885SLC22A2 3001/4885SLC22A1 3146/4885 |
| US-20250228243-A1 | METHODS AND COMPOSITIONS FOR PPO HERBICIDE TOLERANCE | UNG, PNPO, PPOX | SLC6A4 895/4885SLC22A2 2964/4885SLC22A1 3082/4885 |
| US-20250024837-A1 | PESTICIDE SYSTEM | ACHE, PFAS, FPGS | SLC6A4 4377/4885SLC22A2 4274/4885SLC22A1 4400/4885 |
| US-20100234226-A1 | HERBICIDE COMBINATION COMPRISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES | DDT, CBR3, AS3MT | SLC6A4 2025/4885SLC22A2 1878/4885SLC22A1 2017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.