Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 18/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12117067 | 0.89 | SLC2A1 (0.39) | — | |
| SCHEMBL2138881 | 0.89 | P2RX7 (0.39) | — | |
| SCHEMBL12113203 | 0.89 | OPRL1 (0.35) | KLKB1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL2296043 | 0.89 | KLKB1 (0.42) | KLKB1 | |
| SCHEMBL12113393 | 0.88 | SLC2A1 (0.36) | KLKB1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL782240 | 0.88 | SLC2A1 (0.38) | KLKB1 | |
| SCHEMBL11893156 | 0.86 | SLC2A1 (0.37) | KLKB1 | |
| SCHEMBL960289 | 0.86 | SLC2A1 (0.42) | KLKB1 | |
| SCHEMBL31059991 | 0.86 | SLC2A1 (0.42) | KLKB1 | |
| SCHEMBL13084936 | 0.86 | P2RX7 (0.35) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090133318-A1 | Anthranilamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-05-28 | — | — | US | claimed |
| EP-1812421-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-08-01 | — | — | EP | claimed |
| WO-2006055922-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-05-26 | — | — | WO | claimed |
| EP-2564706-A1 | Anthranilamide insecticides | E. I. du Pont de Nemours and Company (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20090133318-A1 | Anthranilamide insecticides | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-05-28 | — | — | US | disclosed |
| EP-1812421-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006055922-A2 | ANTHRANILAMIDE INSECTICIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090133318-A1 | Anthranilamide insecticides | C3AR1, C5, C1S | KLKB1 2498/4885PLG 4509/4885PRSS1 2803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.