SCHEMBL782240

SCHEMBL782240

CNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 4/20 0.38
SLC2A3 P11169 4/20 0.38
SLC2A4 P14672 4/20 0.38
SLC2A2 P11168 1/20 0.38
CARM1 Q86X55 1/20 0.37
PDE4B Q07343 2/20 0.37
KLKB1 P03952 6/20 0.36
ELANE P08246 1/20 0.35
F2 P00734 1/20 0.35
F10 P00742 1/20 0.35
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
TRPV1 Q8NER1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12158541 0.93 CARM1 (0.38) SLC2A1SLC2A3SLC2A4SLC2A2CARM1
SCHEMBL10140212 0.93 CARM1 (0.38) SLC2A1SLC2A3SLC2A4SLC2A2CARM1
SCHEMBL11893157 0.93 KLKB1 (0.39) SLC2A1SLC2A3SLC2A4SLC2A2CARM1
SCHEMBL11893156 0.92 SLC2A1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2PDE4B
SCHEMBL960289 0.92 SLC2A1 (0.42) SLC2A1SLC2A3SLC2A4SLC2A2PDE4B
SCHEMBL31059991 0.92 SLC2A1 (0.42) SLC2A1SLC2A3SLC2A4SLC2A2PDE4B
SCHEMBL782144 0.91 KLKB1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2PDE4B
SCHEMBL15906348 0.91 KLKB1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2CARM1
SCHEMBL782368 0.90 CARM1 (0.39) CARM1PDE4BKLKB1F10KMT2A
SCHEMBL12911856 0.90 CARM1 (0.39) CARM1PDE4BKLKB1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090076092-A1 METHOD FOR DISRUPTING REPRODUCTIVE PERFORMANCE OF ARTHROPODS ANNAN ISSAC BILLY 2009-03-19 US claimed
EP-2001300-A2 METHOD FOR DISRUPTING REPRODUCTIVE PERFORMANCE OF ARTHROPODS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-17 EP claimed
WO-2007126636-A2 METHOD FOR DISRUPTING REPRODUCTIVE PERFORMANCE OF ARTHROPODS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-08 WO claimed
US-20210378242-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2021-12-09 US disclosed
US-10405548-B2 Fungicidal compositions SYNGENTA CROP PROTECTION LLC (US) 2019-09-10 US disclosed
EP-2547665-B1 INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2018-07-04 EP disclosed
US-20180168158-A1 ANTHRANILAMIDE SEED TREATMENT COMPOSITIONS AND METHODS OF USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2018-06-21 US disclosed
US-9949482-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, LLC (US) 2018-04-24 US disclosed
US-9826737-B2 Solid formulations of carboxamide arthropodicides E I DU PONT DE NEMOURS AND COMPANY (US) 2017-11-28 US disclosed
US-9771365-B2 Spiroheterocyclic N-oxypiperidines as pesticides SYNGENTA PARTICIPATIONS AG (CH) 2017-09-26 US disclosed
US-9771365-B2 Spiroheterocyclic N-oxypiperidines as pesticides SYNGENTA PARTICIPATIONS AG (CH) 2017-09-26 US disclosed
WO-2008021152-A2 AGRONOMIC METHOD E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-02-21 WO disclosed
US-20070264299-A1 Cyano anthranilamide insecticides FMC CORPORATION 2007-11-15 US disclosed
US-20070244073-A1 Pesticidal Mixtures SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 US disclosed
US-20070244073-A1 Pesticidal Mixtures SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 US disclosed
US-7247647-B2 Cyano anthranilamide insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-24 US disclosed
WO-2007068356-A1 INSECTICIDAL COMPOSITIONS WITH IMPROVED EFFECT BAYER CROPSCIENCE AG (DE) 2007-06-21 WO disclosed
WO-2007020050-A2 BICYCLIC BISAMIDE DERIVATIVES AND USE THEREOF AS INSECTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-02-22 WO disclosed
WO-2007009661-A2 PESTICIDAL MIXTURES CONTAINING BICYCLIC ANTHRANILAMIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-01-25 WO disclosed
US-20060111403-A1 Cyano anthranilamide insecticides FMC CORPORATION 2006-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210378242-A1 FUNGICIDAL COMPOSITIONS PIK3C3, CYP51A1, CYP1B1 SLC2A1 4040/4885SLC2A3 3742/4885SLC2A4 4206/4885
US-20060111403-A1 Cyano anthranilamide insecticides C1S, C5, CBR3 SLC2A1 4133/4885SLC2A3 3822/4885SLC2A4 4217/4885
US-20090076092-A1 METHOD FOR DISRUPTING REPRODUCTIVE PERFORMANCE OF ARTHROPODS NASP, CPS1, CYP11A1 SLC2A1 3551/4885SLC2A3 3468/4885SLC2A4 3688/4885
US-20180168158-A1 ANTHRANILAMIDE SEED TREATMENT COMPOSITIONS AND METHODS OF USE AADAC, ABL2, API5 SLC2A1 4808/4885SLC2A3 4710/4885SLC2A4 4820/4885
US-20070244073-A1 Pesticidal Mixtures ACHE, ATL3, BPHL SLC2A1 4394/4885SLC2A3 4206/4885SLC2A4 4386/4885
US-10405548-B2 Fungicidal compositions PIK3C3, CYP51A1, CYP1B1 SLC2A1 4040/4885SLC2A3 3742/4885SLC2A4 4206/4885
US-20070264299-A1 Cyano anthranilamide insecticides C1S, CBR3, C5 SLC2A1 4310/4885SLC2A3 4290/4885SLC2A4 4527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.