SCHEMBL4155049

SCHEMBL4155049

C=C(C)C(=O)OCCC(O)c1ccc2ccccc2c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.48
HDAC8 Q9BY41 1/20 0.48
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
CYP2D6 P10635 2/20 0.45
AOC3 Q16853 1/20 0.45
CYP1A2 P05177 1/20 0.45
TSHR P16473 1/20 0.45
HIF1A Q16665 1/20 0.45
UGT2B7 P16662 1/20 0.43
GLA P06280 1/20 0.42
HTR1A P08908 3/20 0.41
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ATM Q13315 1/20 0.38
ADRA2A P08913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13801026 0.94 HDAC1 (0.50) HDAC1HDAC8MEN1KMT2ACYP2D6
SCHEMBL13801021 0.83 HPGD (0.44) KMT2ATSHRPOLBAPEX1HTT
Hydrochloric Acid SCHEMBL9656190 0.83 CHRNB2 (0.48) AOC3GLAMTNR1AMTNR1BADRA2A
SCHEMBL29791076 0.82 PPARG (0.46) MEN1KMT2APOLBAPEX1HTT
SCHEMBL13801034 0.81 HDAC1 (0.50) HDAC1HDAC8MEN1KMT2ACYP2D6
SCHEMBL13801028 0.79 TDP1 (0.36) MEN1KMT2ACYP1A2TSHRGLA
SCHEMBL13801024 0.76 MTNR1A (0.39) KMT2ATSHRMTNR1APOLBAPEX1
SCHEMBL13801022 0.76 POLB (0.49) TSHRPOLBAPEX1HTTTDP1
SCHEMBL12383206 0.76 UGT2B7 (0.47) MEN1KMT2ACYP2D6AOC3CYP1A2
SCHEMBL235139 0.75 MTNR1A (0.49) KMT2ACYP2D6CYP1A2TSHRMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101462957-A Aromatic (meth)acrylate compound having an alpha-hydroxy, photosensitive polymer, resist compositions, and associated methods CHEIL IND INC (KR) 2009-06-24 CN disclosed
US-20090155719-A1 Aromatic (meth)acrylate compound having an alpha-hydroxy, photosensitive polymer, resist compositions, and associated methods CHEIL INDUSTRIES, INC. (KR) 2009-06-18 US disclosed
US-20090155719-A1 Aromatic (meth)acrylate compound having an alpha-hydroxy, photosensitive polymer, resist compositions, and associated methods CHEIL INDUSTRIES, INC. (KR) 2009-06-18 US disclosed
US-20090155719-A1 Aromatic (meth)acrylate compound having an alpha-hydroxy, photosensitive polymer, resist compositions, and associated methods CHEIL INDUSTRIES, INC. (KR) 2009-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090155719-A1 Aromatic (meth)acrylate compound having an alpha-hydroxy, photosensitive polymer, resist compositions, and associated methods AHR, PAH, MCHR1 HDAC1 753/4885HDAC8 1801/4885MEN1 908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.