Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219698 | 0.81 | CHRNA7 (0.45) | CHRNB2CHRNA7CHRNA4L3MBTL1CHRM2 | |
| SCHEMBL6178200 | 0.81 | MKNK1 (0.48) | MKNK1CHRNB2CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL716893 | 0.81 | MKNK1 (0.48) | MKNK1CHRNB2CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL25322649 | 0.79 | HRH3 (0.41) | HRH3HRH4LTA4HALDH1A1TSHR | |
| SCHEMBL2110852 | 0.77 | ALDH1A1 (0.49) | MKNK1CHRNB2CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL8611268 | 0.76 | CYP2D6 (0.47) | MKNK1CHRNB2CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL21806676 | 0.75 | CHRNB2 (0.44) | MKNK1CHRNB2CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL1829565 | 0.75 | LTA4H (0.54) | CHRNB2CHRNA7CHRNA4L3MBTL1LTA4H | |
| SCHEMBL7992297 | 0.74 | MKNK1 (0.55) | MKNK1CHRNB2CHRNA7CHRNA4L3MBTL1 | |
| SCHEMBL6179719 | 0.74 | MKNK1 (0.55) | MKNK1CHRNB2CHRNA7CHRNA4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | HSP90AB1, HSP90AA1, HSP90AB2P | MKNK1 1348/4885CHRNB2 4645/4885CHRNA7 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.