SCHEMBL41557

SCHEMBL41557

C=CC(=O)OC(C)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.67
ALDH1A1 P00352 2/20 0.41
TP53 P04637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
THRB P10828 1/20 0.41
CYP2C19 P33261 1/20 0.41
KMT2A Q03164 1/20 0.40
FFAR1 O14842 1/20 0.40
AKT1 P31749 1/20 0.39
LPAR1 Q92633 2/20 0.39
LPAR3 Q9UBY5 1/20 0.39
CYP3A4 P08684 1/20 0.39
LTB4R Q15722 2/20 0.38
LTB4R2 Q9NPC1 2/20 0.38
GABRA1 P14867 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA5 P31644 1/20 0.38
GABRA3 P34903 1/20 0.38
GABRA2 P47869 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28863896 1.00 HCAR2 (0.67) HCAR2ALDH1A1TP53HSD17B10THRB
SCHEMBL28077544 0.95 HCAR2 (0.61) HCAR2ALDH1A1TP53HSD17B10THRB
Maleic Acid SCHEMBL27844223 0.93 HCAR2 (0.79) HCAR2ALDH1A1TP53HSD17B10THRB
Acrylic Acid Methyl Ester SCHEMBL28779332 0.93 HCAR2 (0.59) HCAR2ALDH1A1TP53HSD17B10THRB
Ethylene Glycol SCHEMBL6491857 0.93 HCAR2 (0.59) HCAR2ALDH1A1TP53HSD17B10THRB
Styrene SCHEMBL27904886 0.92 HCAR2 (0.58) HCAR2ALDH1A1TP53HSD17B10THRB
Methacrylic Acid SCHEMBL20875069 0.92 HCAR2 (0.58) HCAR2ALDH1A1TP53HSD17B10THRB
SCHEMBL6536970 0.90 HCAR2 (0.53) HCAR2ALDH1A1TP53HSD17B10THRB
SCHEMBL27132119 0.90 HCAR2 (0.55) HCAR2CYP2C19LPAR1LPAR3
Crotonic Acid SCHEMBL28796206 0.89 HCAR2 (0.68) HCAR2ALDH1A1TP53HSD17B10THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1040 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12611296-B2 Intraocular lens materials and components ALCON INC. (CH) 2026-04-28 US claimed
CN-119431642-A Resin particle composition, detection kit, and method for producing resin particle composition 赛登化学株式会社 2025-02-14 CN claimed
US-20250043103-A1 RESIN PARTICLE COMPOSITION, TEST KIT, AND MANUFACTURING METHOD OF RESIN PARTICLE COMPOSITION SAIDEN CHEMICAL INDUSTRY CO., LTD. (JP) 2025-02-06 US claimed
EP-4501971-A1 RESIN PARTICLE COMPOSITION, TEST KIT, AND MANUFACTURING METHOD OF RESIN PARTICLE COMPOSITION Saiden Chemical Industry Co., Ltd. (JP) 2025-02-05 EP claimed
US-20240350256-A1 INTRAOCULAR LENS MATERIALS AND COMPONENTS ALCON INC. (CH) 2024-10-24 US claimed
US-12059342-B2 Intraocular lens materials and components ALCON INC. (CH) 2024-08-13 US claimed
US-20240142665-A1 OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2024-05-02 US claimed
US-20240117092-A1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2024-04-11 US claimed
EP-4284787-A1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2023-12-06 EP claimed
EP-4263513-A1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2023-10-25 EP claimed
EP-0733452-A2 Improved cured composite and process therefor ROHM AND HAAS COMPANY (US) 1996-09-25 EP claimed
US-5485541-A MOLTEN CLADDING POLYMER, CROSSLINKED ACRYLIC POLYMER CORE ROHM AND HAAS COMPANY (US) 1996-01-16 US claimed
US-5470932-A Polymerizable yellow dyes and their use in opthalmic lenses ALCON LABORATORIES, INC. (US) 1995-11-28 US claimed
EP-0674684-A1 POLYMERISABLE YELLOW DYES AND THEIR USE IN OPHTHALMIC LENSES ALCON LABORATORIES, INC. (US) 1995-10-04 EP claimed
WO-1995011279-A1 POLYMERISABLE YELLOW DYES AND THEIR USE IN OPHTHALMIC LENSES ALCON LABORATORIES, INC. (US) 1995-04-27 WO claimed
US-5406641-A Acrylate core mixture crosslinkable with coextruded fluoro-polymer; heat resistant, good hardness ROHM AND HAAS COMPANY (US) 1995-04-11 US claimed
EP-0629493-A1 A cured composite and a process for producing the cured composite ROHM AND HAAS COMPANY (US) 1994-12-21 EP claimed
US-5290892-A Crosslinked phenylethyl acrylate-phenylethyl methacrylate NESTLE S.A. (CH) 1994-03-01 US claimed
US-5258355-A Graft polymer with unsaturated ester groups forming shells AGFA-GEVAERT AKTIENGESELLSCHAFT 1993-11-02 US claimed
WO-1991018861-A1 2-(HYDROXYMETHYL) ACRYLATE DERIVATIVES AND PROCESS FOR THEIR PREPARATION COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1991-12-12 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240117092-A1 OPTICALLY ACTIVE DEVICES PDE6C, UACA, PDE6A HCAR2 2093/4885ALDH1A1 538/4885TP53 4769/4885
US-12611296-B2 Intraocular lens materials and components CRYAA, AQP4, CRYZ HCAR2 1670/4885ALDH1A1 1483/4885TP53 833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.