Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL296162 | 0.80 | TAAR1 (0.60) | TAAR1MEN1KMT2ACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL8185830 | 0.78 | KDM4E (0.58) | TAAR1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL2091032 | 0.74 | TAAR1 (0.54) | TAAR1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL28651525 | 0.69 | LOXL2 (0.59) | TAAR1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL2504209 | 0.68 | KDM4E (0.68) | TAAR1LOXL2NCF1KDM4ECYP3A4 | |
| SCHEMBL12482249 | 0.67 | LOXL2 (0.45) | MEN1KMT2ATDP1LOXL2NCF1 | |
| SCHEMBL24821237 | 0.67 | KMT2A (0.77) | MEN1KMT2ACYP2C9CYP2C19RAB9A | |
| SCHEMBL2750084 | 0.67 | MEN1 (0.58) | MEN1KMT2ACYP2C9CYP2C19RAB9A | |
| SCHEMBL6077220 | 0.66 | SMN1; SMN2 (0.50) | TAAR1MEN1KMT2ACYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL30925271 | 0.66 | KDM4E (0.74) | TAAR1LOXL2NCF1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090076081-A1 | PIPERIDINE DERIVATIVES AS NK3 ANTAGONISTS | HOFFMANN-LA ROCHE, INC. | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090076081-A1 | PIPERIDINE DERIVATIVES AS NK3 ANTAGONISTS | DRD2, DRD3, OPRL1 | TAAR1 210/4885MEN1 4790/4885KMT2A 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.