Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2918933 | 0.81 | KMT2A (0.52) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL13313370 | 0.81 | MEN1 (0.54) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2920152 | 0.80 | PIM1 (0.48) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3364537 | 0.78 | CHRM2 (0.57) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL9422686 | 0.78 | ALDH1A1 (0.51) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2920813 | 0.77 | KMT2A (0.57) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11551062 | 0.76 | KMT2A (0.47) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2918502 | 0.76 | NQO2 (0.45) | KMT2AMEN1MAPTSMN1; SMN2MAOA | |
| SCHEMBL3107938 | 0.75 | ALDH1A1 (0.49) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7877715 | 0.75 | CHRM2 (0.80) | KMT2AMEN1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9127164-B2 | Fluorescent dyes and uses thereof | ALMAC SCIENCES (SCOTLAND) LIMITED (GB) | 2015-09-08 | — | — | US | disclosed |
| EP-1940965-B1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ALMAC SCIENCES SCOTLAND LTD (GB) | 2014-03-26 | — | — | EP | disclosed |
| US-20090226940-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI SCOTLAND LIMITED (GB) | 2009-09-10 | — | — | US | disclosed |
| EP-1940965-A2 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI Scotland Limited (GB) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007049057-A2 | NOVEL FLUORESCENT DYES AND USES THEREOF | ITI SCOTLAND LIMITED (GB) | 2007-05-03 | — | — | WO | disclosed |
| EP-0111205-B1 | ACRIDANONE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1987-04-01 | — | — | EP | disclosed |
| US-4544659-A | PARASITICIDES | HOFFMAN-LA ROCHE INC. (US) | 1985-10-01 | — | — | US | disclosed |
| US-4462993-A | REACTION WITH A SUGAR IN PRESENCE OF ACID CATALYST | BIOGAL GYOGYSZERGYAR (HU) | 1984-07-31 | — | — | US | disclosed |
| EP-0111205-A1 | Acridanone derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-06-20 | — | — | EP | disclosed |
| US-4150231-A | ANTITUMOR AGENTS | POLITECHNIKA GDANSKA (PL) | 1979-04-17 | — | — | US | disclosed |
| US-4139531-A | ANTINEOPLASTIC | POLITECHNIKA GDANSKA (PL) | 1979-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090226940-A1 | NOVEL FLUORESCENT DYES AND USES THEREOF | ACR, ANXA5, GLB1 | KMT2A 4502/4885MEN1 3393/4885MAPT 2114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.