Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14349548 | 0.86 | RAB9A (0.54) | NPC1RAB9ABAZ2ATYRMEN1 | |
| SCHEMBL7531332 | 0.75 | NPC1 (0.56) | NPC1RAB9ABAZ2ATYRMEN1 | |
| SCHEMBL2556748 | 0.73 | NPC1 (0.58) | NPC1RAB9ACFTRMEN1POLB | |
| SCHEMBL8118408 | 0.73 | KDM4E (0.59) | NPC1RAB9AMAOAMAOB | |
| SCHEMBL18466529 | 0.73 | IDH2 (0.45) | KIF11BRD4 | |
| SCHEMBL27885120 | 0.73 | NPC1 (0.42) | NPC1RAB9ABAZ2ATYRMEN1 | |
| Hydrochloric Acid SCHEMBL8824042 | 0.72 | KDM4E (0.58) | NPC1RAB9AMAOAMAOB | |
| SCHEMBL27575993 | 0.71 | ITGB3 (0.54) | NPC1RAB9ABAZ2AMEN1POLB | |
| SCHEMBL2559123 | 0.71 | KDM4E (0.60) | NPC1RAB9ATYRMEN1POLB | |
| SCHEMBL13216767 | 0.71 | RECQL (0.62) | NPC1RAB9APOLBKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069287-A1 | SUBSTITUTED AZACYCLOALKANES USEFUL FOR TREATING CNS CONDITIONS | PFIZER INC | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069287-A1 | SUBSTITUTED AZACYCLOALKANES USEFUL FOR TREATING CNS CONDITIONS | BACE2, BACE1, PMP22 | NPC1 138/4885RAB9A 1957/4885BAZ2A 738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.