Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.39 |
| ▸ | CNR1 | P21554 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4139156 | 1.00 | CNR2 (0.39) | CNR2CNR1TSHRALDH1A1TP53 | |
| SCHEMBL4153077 | 0.95 | ESR1 (0.35) | CNR2CNR1ALDH1A1CYP3A4 | |
| SCHEMBL4153074 | 0.95 | ESR1 (0.35) | CNR2CNR1ALDH1A1CYP3A4 | |
| SCHEMBL4143066 | 0.93 | MTNR1A (0.37) | CNR2CNR1TSHRALDH1A1OPRM1 | |
| SCHEMBL4143069 | 0.93 | MTNR1A (0.37) | CNR2CNR1TSHRALDH1A1OPRM1 | |
| SCHEMBL4153609 | 0.92 | MAPT (0.39) | CNR2CNR1ALDH1A1TP53OPRM1 | |
| SCHEMBL4153607 | 0.92 | MAPT (0.39) | CNR2CNR1ALDH1A1TP53OPRM1 | |
| SCHEMBL4139869 | 0.91 | OPRM1 (0.36) | CNR2CNR1OPRM1OPRD1OPRK1 | |
| SCHEMBL4139872 | 0.91 | OPRM1 (0.36) | CNR2CNR1OPRM1OPRD1OPRK1 | |
| SCHEMBL4152682 | 0.90 | PRKCA (0.39) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2009-05-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090136449-A1 | Tetracyclic Indole Derivatives as Antiviral Agents | IDO1, IDO2, ZC3HAV1 | CNR2 248/4885CNR1 127/4885TSHR 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.