Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 8/20 | 0.47 |
| ▸ | CBX7 | O95931 | 2/20 | 0.46 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.46 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.46 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621007 | 0.88 | POLB (0.51) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL4174395 | 0.81 | ALDH1A1 (0.48) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL4620748 | 0.81 | LMNA (0.40) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL5125260 | 0.80 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL4160412 | 0.79 | HTT (0.46) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL3507991 | 0.79 | ALDH1A1 (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL4164026 | 0.79 | ALDH1A1 (0.54) | CYP1A2CYP3A4CYP2D6CYP2C19POLB | |
| SCHEMBL4156192 | 0.78 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C19CBX7CDYL2 | |
| Trifluoroacetic Acid SCHEMBL4622701 | 0.76 | CHRM1 (0.46) | — | |
| SCHEMBL4166185 | 0.76 | NPC1 (0.42) | CYP1A2CYP3A4CYP2D6CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | CYP1A2 2863/4885CYP3A4 3542/4885CYP2D6 3094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.