SCHEMBL415657

SCHEMBL415657

[CH2]C(O)COCCCCC

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.59
HTT P42858 2/20 0.57
SPHK1 Q9NYA1 1/20 0.52
LPAR5 Q9H1C0 4/20 0.49
MEN1 O00255 1/20 0.45
THRB P10828 1/20 0.45
KMT2A Q03164 1/20 0.45
MAPT P10636 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C19 P33261 1/20 0.45
LPAR1 Q92633 7/20 0.44
LPAR3 Q9UBY5 7/20 0.44
LPAR2 Q9HBW0 4/20 0.44
LPAR6 P43657 3/20 0.44
LPAR4 Q99677 3/20 0.44
PLA2G2C Q5R387 1/20 0.43
HSD17B10 Q99714 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272928 0.98 USP2 (0.62) USP2HTTSPHK1LPAR5MEN1
SCHEMBL7751077 0.98 USP2 (0.62) USP2HTTSPHK1LPAR5MEN1
SCHEMBL4933530 0.98 USP2 (0.62) USP2HTTSPHK1LPAR5MEN1
SCHEMBL4931890 0.98 USP2 (0.62) USP2HTTSPHK1LPAR5MEN1
SCHEMBL4927093 0.98 USP2 (0.62) USP2HTTSPHK1LPAR5MEN1
SCHEMBL8756384 0.98 USP2 (0.62) USP2HTTSPHK1LPAR5MEN1
SCHEMBL4932566 0.98 USP2 (0.62) USP2HTTSPHK1LPAR5MEN1
SCHEMBL4930730 0.98 USP2 (0.62) USP2HTTSPHK1LPAR5MEN1
SCHEMBL4926580 0.98 USP2 (0.62) USP2HTTSPHK1LPAR5MEN1
SCHEMBL8756462 0.98 USP2 (0.62) USP2HTTSPHK1LPAR5MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170204077-A1 Method of Producing Epoxy Compound and Catalyst Composition for Epoxidation Reaction MITSUBISHI CHEMICAL CORPORATION (JP) 2017-07-20 US claimed
CN-104203933-A Process for producing epoxy compound and catalyst composition for epoxidation reaction MITSUBISHI CHEM CORP 2014-12-10 CN claimed
US-6019925-A TERTIARY AMINE OXIDE AKZO NOBEL NV (NL) 2000-02-01 US claimed
EP-0807460-A1 Cellulosic dialysis membrane Akzo Nobel N.V. (NL) 1997-11-19 EP claimed
EP-0352863-A2 1,4-Dihydropyridine dicarboxylic acid derivatives ZAMBON GROUP S.p.A. (IT) 1990-01-31 EP claimed
EP-0065864-B1 ANTI-HYPERTENSIVE 1-SUBSTITUTED SPIRO (PIPERIDINE-OXOBENZOXAZINES) SYNTEX (U.S.A.) INC. (US) 1985-08-28 EP claimed
EP-0065864-A1 Anti-hypertensive 1-substituted spiro (piperidine-oxobenzoxazines) SYNTEX (U.S.A.) INC. (US) 1982-12-01 EP claimed
US-4349549-A Anti-hypertensive 1-substituted spiro(piperidine-oxobenzoxazine)s SYNTEX (U.S.A.) INC. (US) 1982-09-14 US claimed
EP-0005318-A1 N-Heterocyclyl-4-piperidinamines, methods for their preparation, pharmaceutical compositions comprising them, intermediates therefor, and method for the preparation of the intermediates JANSSEN PHARMACEUTICA N.V. (BE) 1979-11-14 EP claimed
JP-2078661-A None JP disclosed
US-11958802-B2 Migration-resistant photopolymerization sensitizer KAWASAKI KASEI CHEMICALS LTD. (JP) 2024-04-16 US disclosed
CN-113166036-B Photopolymerizing sensitizers with migration resistance 川崎化成工业株式会社 2023-10-10 CN disclosed
CN-115128901-A Photosensitive resin composition, cured product, printed wiring board, and method for producing printed wiring board 太阳油墨制造株式会社 2022-09-30 CN disclosed
CN-114763453-A Surface protective film, optical member including the same, and display apparatus including the same 三星SDI株式会社 2022-07-19 CN disclosed
EP-0065864-A1 Anti-hypertensive 1-substituted spiro (piperidine-oxobenzoxazines) SYNTEX (U.S.A.) INC. (US) 1982-12-01 EP disclosed
US-4349549-A Anti-hypertensive 1-substituted spiro(piperidine-oxobenzoxazine)s SYNTEX (U.S.A.) INC. (US) 1982-09-14 US disclosed
US-4349549-A Anti-hypertensive 1-substituted spiro(piperidine-oxobenzoxazine)s SYNTEX (U.S.A.) INC. (US) 1982-09-14 US disclosed
US-4219559-A N-Heterocyclyl-4-piperidinamines JANSSEN PHARMACEUTICA N.V. (BE) 1980-08-26 US disclosed
US-4181802-A ADRENERGIC BLOCKING AGENTS JANSSEN PHARMACEUTICA N.V. (BE) 1980-01-01 US disclosed
EP-0005610-A2 1-(Heterocyclylalkyl)-1,3-dihydro-2H-benzimidazol-2-ones, their preparation, their pharmaceutical compositions and their use as beta-adrenergic receptor blockers JANSSEN PHARMACEUTICA N.V. (BE) 1979-11-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958802-B2 Migration-resistant photopolymerization sensitizer F12, F10, PCNA USP2 2545/4885HTT 1272/4885SPHK1 1796/4885
US-20170204077-A1 Method of Producing Epoxy Compound and Catalyst Composition for Epoxidation Reaction EPX, MPO, NOX5 USP2 2237/4885HTT 4462/4885SPHK1 1287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.