SCHEMBL4156778

SCHEMBL4156778

Cn1nc(-c2cc(O)c(Cl)cc2F)c(Cl)c1OC(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7160104 0.86 SLC34A1 (0.32)
SCHEMBL6289042 0.85 SCN9A (0.35)
SCHEMBL8428795 0.85 PRKDC (0.31)
SCHEMBL8299245 0.85 AR (0.30)
SCHEMBL6295368 0.84 PDE10A (0.33)
SCHEMBL4067916 0.83 NTRK1 (0.35)
SCHEMBL7974134 0.83 NTRK1 (0.33)
SCHEMBL8432907 0.83 HSD11B1 (0.31)
SCHEMBL7175397 0.83
SCHEMBL8474283 0.82 ESR1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4353082-A1 HERBICIDAL COMPOSITIONS Bayer Aktiengesellschaft (DE) 2024-04-17 EP disclosed
US-20090029857-A1 Synergistic Herbicidal Compositions ISAGRO RICERCA S.R.L. (IT) 2009-01-29 US disclosed
EP-1998616-A1 NEW SYNERGISTIC HERBICIDAL COMPOSITIONS Isagro Ricerca S.r.l. (IT) 2008-12-10 EP disclosed
WO-2007101587-A1 NEW SYNERGISTIC HERBICIDAL COMPOSITIONS ISAGRO RICERCA S.R.L. (IT) 2007-09-13 WO disclosed
EP-1020448-B1 Arylheterocycles with herbicidal activity ISAGRO RICERCA SRL (IT) 2005-02-16 EP disclosed
WO-2004072065-A1 NOVEL OXYGEN CONTAINING FUSED CYCLIC DERIVATIVES AND HERBIDICAL, DESICCANT AND DEFOLIATE COMPOSITIONS CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 2004-08-26 WO disclosed
US-20040157738-A1 Novel oxygen containing fused cyclic derivatives and herbicidal, desiccant and defoliate compositions containing them ISHIHARA SANGYO KAISHA, LTD. 2004-08-12 US disclosed
US-20040029734-A1 Fused-benzene derivatives useful as herbicides ISHIHARA SANGYO KAISHA, LTD. 2004-02-12 US disclosed
US-6573218-B1 Defoliants containing such as uracil and 1,4-benzoxazole or benzthiazole moieties ISHIHARA SANGYO KAISHA, LTD. (JP) 2003-06-03 US disclosed
EP-1074551-B1 Phenylpyrazoles with a herbicidal activity ISAGRO RICERCA SRL (IT) 2003-03-26 EP disclosed
EP-1111993-A4 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA (JP) 2002-12-04 EP disclosed
US-6303543-B1 Diaryl ethers and processes for their preparation and herbicidal and desiccant compositions containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 2001-10-16 US disclosed
US-6265351-B1 CONTROLLING WEEDS IN THE AGRONOMIC FIELD. ISAGRO RICERCA S.R.L. (IT) 2001-07-24 US disclosed
EP-1111993-A1 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA, LTD. (JP) 2001-07-04 EP disclosed
EP-1074551-A2 Phenylpyrazoles with a herbicidal activity Isagro Ricerca S.r.l. (IT) 2001-02-07 EP disclosed
US-6121201-A HETEROARYL SUBSTITUTED HALO-PYRAZOLE SUBSTITUTED DIARYL ETHERS OR THIOETHERS ISHIHARA SANGYO KAISHA, LTD. (JP) 2000-09-19 US disclosed
EP-1020448-A2 Arylheterocycles with herbicidal activity Isagro Ricerca S.r.l. (IT) 2000-07-19 EP disclosed
WO-2000013508-A1 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA, LTD. (JP) 2000-03-16 WO disclosed