SCHEMBL8428795

SCHEMBL8428795

Cn1nc(-c2cc(C(F)F)c(Cl)cc2F)c(Cl)c1OC(F)F

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.31
KCNH2 Q12809 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7175397 0.90
SCHEMBL8430759 0.88
SCHEMBL8429562 0.86
SCHEMBL7160104 0.86 SLC34A1 (0.32)
SCHEMBL6289042 0.85 SCN9A (0.35)
SCHEMBL4156778 0.85
SCHEMBL6295368 0.84 PDE10A (0.33) PRKDC
SCHEMBL27469166 0.84 PPOX (0.32)
SCHEMBL8432907 0.83 HSD11B1 (0.31)
SCHEMBL7162428 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5962694-A Substituted 1-methyl-3-phenylpyrazoles and the use thereof as herbicides and for the desiccation or defoliation of plants BASF AKTIENGESELLSCHAFT (DE) 1999-10-05 US disclosed
EP-0861237-A1 SUBSTITUTED 1-METHYL-3-PHENYLPYRAZOLES AND THE USE THEREOF AS HERBICIDES AND FOR THE DESICCATION OR DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 1998-09-02 EP disclosed
WO-1997018195-A1 SUBSTITUTED 1-METHYL-3-PHENYLPYRAZOLES AND THE USE THEREOF AS HERBICIDES AND FOR THE DESICCATION OR DEFOLIATION OF PLANTS BASF AKTIENGESELLSCHAFT (DE) 1997-05-22 WO disclosed