SCHEMBL4067916

SCHEMBL4067916

Cn1nc(-c2cc(C(=O)O)c(Cl)cc2F)c(Cl)c1OC(F)F

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NTRK1 P04629 20/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27559405 0.92 NTRK1 (0.35) NTRK1
SCHEMBL7974134 0.91 NTRK1 (0.33) NTRK1
SCHEMBL7829990 0.91 TSHR (0.34) NTRK1
SCHEMBL27559404 0.91 PDE5A (0.36) NTRK1
SCHEMBL9856930 0.89 GAA (0.35) NTRK1
SCHEMBL6433878 0.87 SMN1; SMN2 (0.33) NTRK1
SCHEMBL9856794 0.86 BAZ2B (0.40)
SCHEMBL7960698 0.86 NTRK1 (0.36) NTRK1
SCHEMBL7994105 0.86 NTRK1 (0.32) NTRK1
SCHEMBL7994106 0.86 NTRK1 (0.32) NTRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1998038169-A1 SUBSTITUTED 3-PHENYL PYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 1998-09-03 WO claimed
EP-1226127-B1 SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES BASF SE (DE) 2009-07-01 EP disclosed
US-6849618-B2 Uracil substituted phenyl sulfamoly carboxamides BASF AKTIENGESELLSCHAFT (DE) 2005-02-01 US disclosed
US-20040220172-A1 Herbicidal compositions for the desiccation/ defoliation of plants CARLSEN MARIANNE 2004-11-04 US disclosed
US-6689773-B2 HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 2004-02-10 US disclosed
US-20030224941-A1 Uracil substituted phenyl sulfamoyl carboxamides CARLSEN MARIANNE (US) 2003-12-04 US disclosed
US-6534492-B2 Herbicidal phenylsulfamoyl carboxamides BASF AKTIENGESELLSCHAFT (DE) 2003-03-18 US disclosed
EP-0915853-B1 SUBSTITUTED 3-PHENYL PYRAZOLES BASF AG (DE) 2002-11-06 EP disclosed
EP-1226127-A2 URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES BASF AKTIENGESELLSCHAFT (DE) 2002-07-31 EP disclosed
US-20020045550-A1 Uracil substituted phenyl sulfamoyl carboxamides INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) 2002-04-18 US disclosed
US-5962694-A Substituted 1-methyl-3-phenylpyrazoles and the use thereof as herbicides and for the desiccation or defoliation of plants BASF AKTIENGESELLSCHAFT (DE) 1999-10-05 US disclosed
EP-0915853-A1 SUBSTITUTED 3-PHENYL PYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 1999-05-19 EP disclosed
WO-1998038169-A1 SUBSTITUTED 3-PHENYL PYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 1998-09-03 WO disclosed
WO-1998038169-A1 SUBSTITUTED 3-PHENYL PYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 1998-09-03 WO disclosed
EP-0443059-B1 3-(Substituted phenyl)pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO LTD (JP) 1998-06-17 EP disclosed
EP-0361114-B1 3-(Substituted phenyl) pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO LTD (JP) 1998-06-03 EP disclosed
WO-1998005649-A1 SUBSTITUTED 3-PHENYL PYRAZOLES BASF AKTIENGESELLSCHAFT (DE) 1998-02-12 WO disclosed
EP-0443059-A1 3-(Substituted phenyl)pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1991-08-28 EP disclosed
US-5032165-A 3-(substituted phenyl)pyrazole derivatives, salts thereof, and herbicides therefrom NIHON NOHYAKU COMPANY, LTD. (JP) 1991-07-16 US disclosed
EP-0361114-A1 3-(Substituted phenyl) pyrazole derivatives, salts thereof, herbicides therefrom, and process for producing said derivatives or salts NIHON NOHYAKU CO., LTD. (JP) 1990-04-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020045550-A1 Uracil substituted phenyl sulfamoyl carboxamides CCNH, CBR3, UNG NTRK1 4564/4885
US-20030224941-A1 Uracil substituted phenyl sulfamoyl carboxamides CCNH, CBR3, UNG NTRK1 4564/4885
US-20040220172-A1 Herbicidal compositions for the desiccation/ defoliation of plants CBR3, HDHD5, DDAH1 NTRK1 4646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.