Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 12/20 | 0.42 |
| ▸ | DRD4 | P21917 | 11/20 | 0.42 |
| ▸ | DRD3 | P35462 | 10/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | CCND1 | P24385 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4153889 | 0.84 | CCNE1 (0.46) | CCNT1CDK4CCND1CCNE1CDK2 | |
| SCHEMBL4147310 | 0.83 | MAPK14 (0.44) | CCNT1CDK4CCND1CCNE1CDK2 | |
| SCHEMBL3677019 | 0.83 | CCNE1 (0.62) | CCNT1CDK4CCND1CCNE1CDK2 | |
| SCHEMBL3670838 | 0.83 | CCNE1 (0.62) | CCNT1CDK4CCND1CCNE1CDK2 | |
| SCHEMBL3675280 | 0.82 | CCNE1 (0.49) | CCNT1CDK4CCND1CCNE1CDK2 | |
| SCHEMBL3670193 | 0.81 | CCNE1 (0.55) | CCNT1CDK4CCND1CCNE1CDK2 | |
| SCHEMBL4137710 | 0.81 | PIK3CA (0.40) | CCNT1CDK4CCND1CCNE1CDK2 | |
| SCHEMBL3675486 | 0.81 | CCNE1 (0.48) | BCHEACHECCNT1CDK4CCND1 | |
| SCHEMBL3669488 | 0.80 | CCNE1 (0.52) | CCNT1CDK4CCND1CCNE1CDK2 | |
| SCHEMBL3669490 | 0.80 | CDK2 (0.46) | BCHEACHECCNT1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221600-A1 | PYRIDO-PYRIDIMIDINE DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221600-A1 | PYRIDO-PYRIDIMIDINE DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | PNPO, TPMT, NOD1 | DRD2 1844/4885DRD4 1534/4885DRD3 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.