Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 19/20 | 0.46 |
| ▸ | CDK2 | P24941 | 19/20 | 0.46 |
| ▸ | CCND1 | P24385 | 18/20 | 0.46 |
| ▸ | CDK6 | Q00534 | 18/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.46 |
| ▸ | CDK9 | P50750 | 4/20 | 0.46 |
| ▸ | CDK4 | P11802 | 3/20 | 0.46 |
| ▸ | CCND3 | P30281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4145055 | 0.87 | CCNE1 (0.44) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL4137710 | 0.86 | PIK3CA (0.40) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL3669459 | 0.85 | CCNE1 (0.67) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL4147310 | 0.85 | MAPK14 (0.44) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL4157046 | 0.84 | DRD2 (0.42) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL4151475 | 0.83 | PIK3CA (0.43) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL3678898 | 0.82 | CCNE1 (0.59) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL3674341 | 0.81 | CCNE1 (0.72) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL4138454 | 0.80 | CCNE1 (0.58) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL3673672 | 0.80 | CCNE1 (0.68) | CCNE1CDK2CCND1CDK6CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221600-A1 | PYRIDO-PYRIDIMIDINE DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221600-A1 | PYRIDO-PYRIDIMIDINE DERIVATIVES USEFUL AS ANTIINFLAMMATORY AGENTS | PNPO, TPMT, NOD1 | CCNE1 863/4885CDK2 393/4885CCND1 539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.