Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139048 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MAPTNPSR1HSD17B10HPGD | |
| SCHEMBL5143932 | 0.79 | DRD4 (0.47) | ALDH1A1HSD17B10HPGDTSHRLMNA | |
| SCHEMBL5513100 | 0.79 | DRD4 (0.47) | ALDH1A1HSD17B10HPGDTSHRLMNA | |
| SCHEMBL10856673 | 0.78 | HPGD (0.54) | ALDH1A1MAPTNPSR1HSD17B10HPGD | |
| SCHEMBL27834850 | 0.77 | CYP2C9 (0.50) | ALDH1A1MAPTNPSR1HSD17B10HPGD | |
| SCHEMBL18541672 | 0.76 | MEN1 (0.48) | ALDH1A1MAPTNPSR1HSD17B10HPGD | |
| SCHEMBL4151711 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPTNPSR1HSD17B10HPGD | |
| SCHEMBL29418063 | 0.76 | DRD4 (0.38) | ALDH1A1MAPTNPSR1HSD17B10HPGD | |
| SCHEMBL4758994 | 0.75 | SLC6A2 (0.47) | DRD4 | |
| SCHEMBL12961753 | 0.74 | HPGD (0.77) | ALDH1A1NPSR1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754613-B | Method for benzene thio cyclic ether of 4-enol | 北京工商大学 | 2023-06-30 | — | — | CN | disclosed |
| CN-113754613-A | Method for etherifying thiophenyl ring of 3-enol | 北京工商大学 | 2021-12-07 | — | — | CN | disclosed |
| US-20090048203-A1 | SUBSTITUTED ADENINES AND THE USES THEREOF | ASTRAZENECA AB (SE) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048203-A1 | SUBSTITUTED ADENINES AND THE USES THEREOF | HPRT1, APRT, NUDT1 | ALDH1A1 355/4885MAPT 4388/4885NPSR1 2095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.