SCHEMBL4157320

SCHEMBL4157320

CCCc1cc(C(C)c2cc(CCC)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.46
KMT2A Q03164 3/20 0.46
HSPA5 P11021 1/20 0.44
ALDH1A1 P00352 7/20 0.42
TSHR P16473 4/20 0.42
LMNA P02545 2/20 0.42
CYP1A2 P05177 3/20 0.41
CYP3A4 P08684 3/20 0.41
MAPK1 P28482 3/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
MEN1 O00255 2/20 0.41
BLM P54132 2/20 0.41
ATM Q13315 2/20 0.41
HIF1A Q16665 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
GMNN O75496 1/20 0.41
GABBR2 O75899 1/20 0.41
TP53 P04637 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3678954 0.90 GAA (0.43) GAAKMT2AHSPA5ALDH1A1TSHR
SCHEMBL6393895 0.88 PTGS2 (0.47) GAAKMT2AHSPA5ALDH1A1TSHR
SCHEMBL3219897 0.86 HSPA5 (0.59) GAAKMT2AHSPA5ALDH1A1TSHR
SCHEMBL3163975 0.86 TSHR (0.45) GAAKMT2AHSPA5ALDH1A1TSHR
SCHEMBL6394388 0.85 TSHR (0.52) GAAKMT2AHSPA5ALDH1A1TSHR
SCHEMBL4158421 0.84 GAA (0.41) GAAKMT2AHSPA5ALDH1A1TSHR
SCHEMBL14002950 0.84 ALDH1A1 (0.43) GAAKMT2AHSPA5ALDH1A1TSHR
SCHEMBL163700 0.84 GAA (0.58) GAAKMT2AHSPA5ALDH1A1TSHR
SCHEMBL2718090 0.84 GAA (0.40) GAAKMT2AHSPA5ALDH1A1TSHR
SCHEMBL14000550 0.83 ALDH1A1 (0.47) GAAKMT2AHSPA5ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240166672-A1 PHOSPHOROUS ESTER COMPOUND, METHOD FOR PRODUCING SAME AND USE APPLICATION FOR SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2024-05-23 US disclosed
EP-4317166-A1 PHOSPHOROUS ESTER COMPOUND, METHOD FOR PRODUCING SAME, AND USE APPLICATION FOR SAME Sumitomo Chemical Company Limited (JP) 2024-02-07 EP disclosed
WO-2022210295-A1 PHOSPHOROUS ESTER COMPOUND, METHOD FOR PRODUCING SAME, AND USE APPLICATION FOR SAME 住友化学株式会社 2022-10-06 WO disclosed
US-8536258-B2 Stabilizer and method of manufacturing the same, thermoplastic polymer composition using the same, and method of stabilizing thermoplastic polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-09-17 US disclosed
US-20090030127-A1 Stabilizer and method of manufacturing the same, thermoplastic polymer composition using the same, and method of stabilizing thermoplastic polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2009-01-29 US disclosed
EP-2017299-A1 Stabilizer and method of manufacturing the same, thermoplastic polymer composition using the same, and method of stabilizing thermoplastic polymer Sumitomo Chemical Company, Limited (JP) 2009-01-21 EP disclosed
US-20050247913-A1 Phosphorous ester compound, process for producing the same, and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-11-10 US disclosed
US-20040225145-A1 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED 2004-11-11 US disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5891939-A POLYMER STABILIZERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-06 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
US-5874494-A DETERIORATION STABILIZER FOR THERMOPLASTIC RESIN; OXIDATION RESISTANCE, DISCOLORATION INHIBITION, HEAT RESISTANCE, CROSSLINKING INHIBITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-23 US disclosed
US-5847187-A Organic phosphorous compound, a process for producing the same and a use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-08 US disclosed
US-5830936-A THERMAL STABILIZERS FOR POLYOLEFINS AND ENGINEERING PLASTICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-11-03 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed
EP-0500323-B1 Production of bisphenol monoester SUMITOMO CHEMICAL CO (JP) 1997-01-15 EP disclosed
EP-0697393-A2 Production of bisphenol monoester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-21 EP disclosed
US-5214193-A Coupling a dialkylphenol with aldehyde, esterification, crystallization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-25 US disclosed
EP-0500323-A2 Production of bisphenol monoester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240166672-A1 PHOSPHOROUS ESTER COMPOUND, METHOD FOR PRODUCING SAME AND USE APPLICATION FOR SAME EBPL, ACSL6, ACSL3 GAA 2834/4885KMT2A 2699/4885HSPA5 4448/4885
US-20040225145-A1 Process for producing phosphite PHOSPHO1, PLCG1, PLCG2 GAA 3798/4885KMT2A 3796/4885HSPA5 4485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.