Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 15/20 | 0.50 |
| ▸ | MAPT | P10636 | 11/20 | 0.50 |
| ▸ | MEN1 | O00255 | 11/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.50 |
| ▸ | CASP1 | P29466 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.49 |
| ▸ | HPGD | P15428 | 7/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 7/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2614831 | 0.67 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL4045538 | 0.67 | ALDH1A1 (0.68) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL5011418 | 0.65 | ALDH1A1 (0.64) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL4218522 | 0.64 | KRAS (0.56) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL4051254 | 0.63 | ALDH1A1 (0.64) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL4709484 | 0.62 | ALDH1A1 (1.00) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL1719562 | 0.59 | ALDH1A1 (0.57) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL20254479 | 0.59 | BPTF (0.51) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL24862718 | 0.58 | PNMT (0.47) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL26264111 | 0.58 | ALDH1A1 (0.36) | ALDH1A1MAPTMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090029955-A1 | Pyridothienopyrimidine Derivatives | ALMIRALL PRODESFARMA S.A. (ES) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029955-A1 | Pyridothienopyrimidine Derivatives | PNPO, PDE4A, DPYD | ALDH1A1 391/4885MAPT 2618/4885MEN1 3276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.