Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 1.00 |
| ▸ | MEN1 | O00255 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 8/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 1.00 |
| ▸ | CASP1 | P29466 | 5/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | CASP7 | P55210 | 3/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 0.74 |
| ▸ | GAA | P10253 | 3/20 | 0.74 |
| ▸ | THRB | P10828 | 1/20 | 0.74 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045538 | 0.80 | ALDH1A1 (0.68) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL4051254 | 0.78 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL5011418 | 0.72 | ALDH1A1 (0.64) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL2614831 | 0.72 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL10016599 | 0.69 | ALDH1A1 (1.00) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL4218522 | 0.68 | KRAS (0.56) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL15571329 | 0.63 | CUL4A (1.00) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL4157376 | 0.62 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL14318241 | 0.61 | KDM4E (0.62) | ALDH1A1KDM4EMEN1KMT2AHSD17B10 | |
| SCHEMBL4923976 | 0.61 | ALDH1A1 (0.52) | ALDH1A1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9540389-B2 | Antimicrobial potentiators | MICROBIOTIX, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-9540389-B2 | Antimicrobial potentiators | MICROBIOTIX, INC. (US) | 2017-01-10 | — | — | US | disclosed |
| US-20160075714-A1 | Antimicrobial Potentiators | MICROBIOTIX, INC. (US) | 2016-03-17 | — | — | US | disclosed |
| WO-2014179784-A2 | ANTIMICROBIAL POTENTIATORS | MICROBIOTIX, INC. (US) | 2014-11-06 | — | — | WO | disclosed |
| US-20080221096-A1 | Pyrido[3' ,2':4,5]Furo[3,2-d]Pyrimidine Derivatives | LABORATORIOS ALMIRALL, S.A. (ES) | 2008-09-11 | — | — | US | disclosed |
| US-20080207645-A1 | Pyridothienopyrimidine Derivatives | PAGES SANTACANA LUIS MIGUEL | 2008-08-28 | — | — | US | disclosed |
| EP-1913003-A1 | NEW PYRIDO[3',2':4,5]FURO[3,2-d]PYRIMIDINE DERIVATIVES | Laboratorios Almirall, S.A. (ES) | 2008-04-23 | — | — | EP | disclosed |
| EP-1819712-A1 | NEW PYRIDOTHIENOPYRIMIDINE DERIVATIVES | Laboratorios Almirall, S.A. (ES) | 2007-08-22 | — | — | EP | disclosed |
| WO-2007017078-A1 | NEW PYRIDO[3',2':4,5]FURO[3,2-d]PYRIMIDINE DERIVATIVES | LABORATORIOS ALMIRALL, S.A. (ES) | 2007-02-15 | — | — | WO | disclosed |
| WO-2006058723-A1 | NEW PYRIDOTHIENOPYRIMIDINE DERIVATIVES | LABORATORIOS ALMIRALL, S.A. (ES) | 2006-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207645-A1 | Pyridothienopyrimidine Derivatives | PDE4A, PDE5A, PDE3B | ALDH1A1 438/4885KDM4E 1526/4885MAPT 3431/4885 |
| US-20080221096-A1 | Pyrido[3' ,2':4,5]Furo[3,2-d]Pyrimidine Derivatives | NR1H2, CBR3, NR4A1 | ALDH1A1 2625/4885KDM4E 3618/4885MAPT 4743/4885 |
| US-20160075714-A1 | Antimicrobial Potentiators | NR1H2, ABCC5, NR1H3 | ALDH1A1 4200/4885KDM4E 3407/4885MAPT 4881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.