SCHEMBL415739

SCHEMBL415739

Fc1cccc(C(F)(F)F)n1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.44
NOTUM Q6P988 2/20 0.43
IDH1 O75874 8/20 0.42
IDH2 P48735 2/20 0.42
PGK1 P00558 1/20 0.39
PGK2 P07205 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA3 P34903 1/20 0.39
ADRB1 P08588 1/20 0.39
TAS2R14 Q9NYV8 1/20 0.38
AHR P35869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29463867 1.00 P2RX7 (0.44) P2RX7NOTUMIDH1IDH2PGK1
SCHEMBL3295150 0.84 P2RX7 (0.50) P2RX7NOTUMIDH1IDH2PGK1
SCHEMBL10749077 0.81 CYP3A4 (0.40) P2RX7NOTUMPGK1PGK2
SCHEMBL17184335 0.78 CYP3A4 (0.58) P2RX7NOTUMPGK1PGK2
SCHEMBL16472119 0.78 MAPT (0.35) IDH1IDH2PGK1PGK2ADRB1
SCHEMBL2565469 0.78 MAPT (0.35) IDH1IDH2PGK1PGK2ADRB1
SCHEMBL30395354 0.77 NOTUM (0.58) P2RX7NOTUMIDH1IDH2GABRA1
SCHEMBL15624402 0.77 NOTUM (0.58) P2RX7NOTUMIDH1IDH2GABRA1
SCHEMBL19072762 0.75 NOTUM (0.47) NOTUMIDH1IDH2GABRA1GABRG2
SCHEMBL3525189 0.75 PGK1 (0.31) PGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114361590-B Electrolyte additive for lithium ion battery, electrolyte and lithium ion battery 松山湖材料实验室 2023-07-25 CN claimed
CN-109988101-B Synthesis method of 2-fluoro-6-trifluoromethylpyridine 沈阳化工研究院有限公司 2022-06-07 CN claimed
CN-114361590-A Lithium ion battery electrolyte additive, electrolyte and lithium ion battery 松山湖材料实验室 2022-04-15 CN claimed
CN-109988101-A The synthetic method of the fluoro- 6- trifluoromethyl pyridine of 2- 沈阳化工研究院有限公司 2019-07-09 CN claimed
CN-106316933-A Continuous preparation method for 2-fluoro-6-trifluoromethyl pyridine 大连九信精细化工有限公司 2017-01-11 CN claimed
WO-2015151116-A2 PROCESS FOR PRODUCING 2-FLUORO-6-(TRIFLUOROMETHYL)PYRIDINE COMPOUNDS JUBILANT LIFE SCIENCES LIMITED (IN) 2015-10-08 WO claimed
EP-1109788-B1 CHEMICAL PROCESS FOR PREPARING 2-HYDROXY-6-TRIFLUOROMETHYLPYRIDINE SYNGENTA LTD (GB) 2004-01-28 EP claimed
EP-1109788-A1 CHEMICAL PROCESS FOR PREPARING 2-HYDROXY-6-TRIFLUOROMETHYLPYRIDINE Syngenta Limited (GB) 2001-06-27 EP claimed
US-6143899-A REACTING 2-FLUORO-6-TRIFLUOROMETHYLPYRIDINE OR A MIXTURE OF 2-FLUORO-6-TRIFLUOROMETHYLPYRIDINE AND 2-CHLORO-6-TRIFLUOROMETHYLPYRIDINE WITH AN ALKALI METAL HYDROXIDE, HEATING AND ACIDIFYING THE PRODUCT FORMED ZENECA LIMITED (GB) 2000-11-07 US claimed
WO-2000014068-A1 CHEMICAL PROCESS FOR PREPARING 2-HYDROXY-6-TRIFLUOROMETHYLPYRIDINE SYNGENTA LIMITED (GB) 2000-03-16 WO claimed
EP-4731623-A1 CARBOLINE COMPOUNDS AND USE THEREOF PTC Therapeutics, Inc. (US) 2026-04-29 EP disclosed
CN-224156658-U Tubular reactor for absorbing tail gas of 2-fluoro-6-trifluoromethyl pyridine 浙江方华化学有限公司 2026-04-24 CN disclosed
CN-224156658-U Tubular reactor for absorbing tail gas of 2-fluoro-6-trifluoromethyl pyridine 浙江方华化学有限公司 2026-04-24 CN disclosed
EP-4717266-A2 OCTAHYDRO FUSED AZADECALIN GLUCOCORTICOID RECEPTOR MODULATORS Corcept Therapeutics Incorporated (US) 2026-04-01 EP disclosed
US-20260083851-A1 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS AVILAR THERAPEUTICS, INC. (US) 2026-03-26 US disclosed
WO-2000014068-A1 CHEMICAL PROCESS FOR PREPARING 2-HYDROXY-6-TRIFLUOROMETHYLPYRIDINE SYNGENTA LIMITED (GB) 2000-03-16 WO disclosed
WO-2000014068-A1 CHEMICAL PROCESS FOR PREPARING 2-HYDROXY-6-TRIFLUOROMETHYLPYRIDINE SYNGENTA LIMITED (GB) 2000-03-16 WO disclosed
CN-1201032-A Herbicidal 3,5-difluoropyridine AMERICA CYANIDE CO (US) 1998-12-09 CN disclosed
US-4474599-A 1-(Pyridyl)-1H-1,2,3-triazole derivatives, and use as herbicidal agents THE DOW CHEMICAL COMPANY (US) 1984-10-02 US disclosed
US-4203988-A ANTISECRETORY AGENTS MERCK & CO., INC. (US) 1980-05-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083851-A1 POTENT ASGPR-BINDING HETEROBIFUNCTIONAL COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS ASGR1, FCGR2A, FCGR3B P2RX7 1807/4885NOTUM 1938/4885IDH1 3530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.