Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.48 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.48 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.48 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.48 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.48 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.48 |
| ▸ | S100B | P04271 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13997437 | 0.78 | CYP3A4 (0.44) | PDE4APDE4BPDE4CPDE4DCYP19A1 | |
| SCHEMBL1885632 | 0.77 | CYP3A4 (0.46) | PDE4APDE4BPDE4CPDE4DCYP19A1 | |
| SCHEMBL8439508 | 0.76 | CYP3A4 (0.55) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL12391451 | 0.75 | ALDH1A1 (0.57) | PDE4APDE4BPDE4CPDE4DCYP19A1 | |
| SCHEMBL6835451 | 0.74 | MAPT (0.53) | PDE4APDE4BPDE4CPDE4DCYP19A1 | |
| SCHEMBL16983194 | 0.74 | IDO1 (0.61) | PDE4APDE4BPDE4CPDE4DCYP19A1 | |
| SCHEMBL8283425 | 0.74 | CYP3A4 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL29105016 | 0.74 | IDO1 (0.47) | PDE4APDE4BPDE4CPDE4DCYP19A1 | |
| SCHEMBL9260647 | 0.73 | LMNA (0.48) | PDE4APDE4BPDE4CPDE4DCYP19A1 | |
| SCHEMBL11843322 | 0.73 | CYP19A1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215097-A1 | Novel Polymer and Method of Measuring Cholesterol Therewith | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2009-08-27 | — | — | US | disclosed |
| EP-0819765-A2 | Reagent for measuring an amount of cholesterol | WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) | 1998-01-21 | — | — | EP | disclosed |