Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074636 | 0.89 | CYP11B1 (0.48) | CYP11B1CYP11B2CYP19A1TRIM24CYP3A4 | |
| SCHEMBL6074004 | 0.85 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1TRIM24CYP3A4 | |
| SCHEMBL6074045 | 0.83 | CYP11B1 (0.46) | CYP11B1CYP11B2CYP19A1TRIM24CYP3A4 | |
| SCHEMBL12057333 | 0.80 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP19A1TRIM24CYP3A4 | |
| SCHEMBL16431883 | 0.78 | CYP11B1 (0.56) | CYP11B1CYP11B2CYP19A1TRIM24CYP3A4 | |
| SCHEMBL6074490 | 0.78 | CYP11B1 (0.50) | CYP11B1CYP11B2CYP19A1TRIM24CYP3A4 | |
| SCHEMBL4156212 | 0.75 | CYP11B1 (0.48) | CYP11B1CYP11B2CYP19A1TRIM24CYP3A4 | |
| SCHEMBL6073535 | 0.75 | CYP11B1 (0.46) | CYP11B1CYP11B2CYP19A1TRIM24CYP3A4 | |
| SCHEMBL6073506 | 0.74 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1TRIM24CYP3A4 | |
| SCHEMBL23011989 | 0.73 | MAP3K5 (0.45) | CYP11B1CYP11B2CYP19A1TRIM24CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470816-B2 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-06-25 | — | — | US | disclosed |
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156572-A1 | Nitrogen-containing heterocyclic compound and use thereof | NTSR2, NTSR1, HNMT | CYP11B1 528/4885CYP11B2 359/4885CYP19A1 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.