Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.39 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.39 |
| ▸ | MPG | P29372 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | YES1 | P07947 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | IAPP | P10997 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168942 | 0.99 | ALOX5 (0.41) | HTTALOX5ADORA3POLHMPG | |
| SCHEMBL4164234 | 0.99 | ALOX5 (0.41) | HTTALOX5ADORA3POLHMPG | |
| SCHEMBL4163599 | 0.99 | ALOX5 (0.41) | HTTALOX5ADORA3POLHMPG | |
| SCHEMBL4153248 | 0.99 | ALOX5 (0.41) | HTTALOX5ADORA3POLHMPG | |
| SCHEMBL4161249 | 0.99 | ALOX5 (0.41) | HTTALOX5ADORA3POLHMPG | |
| SCHEMBL4162126 | 0.99 | ALOX5 (0.41) | HTTALOX5ADORA3POLHMPG | |
| SCHEMBL4175448 | 0.92 | ADORA3 (0.41) | ALOX5ADORA3POLHMPGKDM4E | |
| SCHEMBL4157272 | 0.89 | ABCB1 (0.46) | ALOX5POLHKDM4EPOLBCYP3A4 | |
| SCHEMBL4158702 | 0.88 | ALOX5 (0.46) | ALOX5POLHKDM4EPOLBCYP3A4 | |
| SCHEMBL4152427 | 0.88 | ALOX5 (0.46) | ALOX5POLHKDM4EPOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2009-05-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | CAT, NQO1, GPX4 | HTT 1877/4885ALOX5 387/4885ADORA3 2776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.