Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.92 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.92 |
| ▸ | HPGD | P15428 | 2/20 | 0.92 |
| ▸ | GAA | P10253 | 1/20 | 0.92 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | RECQL | P46063 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 8/20 | 0.38 |
| ▸ | GMNN | O75496 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | APEX1 | P27695 | 4/20 | 0.38 |
| ▸ | BLM | P54132 | 4/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256433 | 0.96 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL4158039 | 0.86 | KDM4E (0.68) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL4172133 | 0.83 | KDM4E (0.76) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL4166184 | 0.82 | KDM4E (0.70) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL4162722 | 0.82 | KDM4E (0.70) | ALDH1A1KDM4EHPGDGAAMAPT | |
| Iodide SCHEMBL14740354 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL4156549 | 0.81 | KDM4E (0.62) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL9603085 | 0.79 | KDM4E (0.61) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL9704067 | 0.77 | KDM4E (0.60) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL12194203 | 0.77 | MEN1 (0.64) | ALDH1A1KDM4EHPGDGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090252687-A1 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | COOPER MICHAEL EDWARD | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090252687-A1 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | FCGR2A, FCGR3B, FCER2 | ALDH1A1 1730/4885KDM4E 1270/4885HPGD 3280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.