Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 10/20 | 0.38 |
| ▸ | GMNN | O75496 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | APEX1 | P27695 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 4/20 | 0.38 |
| ▸ | BLM | P54132 | 4/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4158036 | 0.86 | ALDH1A1 (0.92) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL4172137 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL4162727 | 0.82 | KDM4E (0.52) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL4166188 | 0.82 | KDM4E (0.52) | KDM4EALDH1A1GAAHPGDMEN1 | |
| Iodide SCHEMBL14740354 | 0.81 | ALDH1A1 (0.65) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL4156552 | 0.81 | ALDH1A1 (0.46) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL7256433 | 0.81 | ALDH1A1 (1.00) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL9603085 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL5684840 | 0.78 | HPGD (0.51) | KDM4EALDH1A1GAAHPGDMEN1 | |
| SCHEMBL455623 | 0.77 | ATM (0.56) | KDM4EALDH1A1GAAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090252687-A1 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | COOPER MICHAEL EDWARD | 2009-10-08 | — | — | US | disclosed |
| US-6579718-B1 | For detecting and quantifying peptides, polypeptides and proteins; sensitive, facile and does not require use of organic solvents | MOLECULAR PROBES, INC. | 2003-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090252687-A1 | ASYMMETRIC FLUORO-SUBSTITUTED POLYMETHINE DYES | FCGR2A, FCGR3B, FCER2 | KDM4E 1270/4885ALDH1A1 1730/4885GAA 2680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.