Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787150 | 0.85 | KIF11 (0.61) | MAPTKIF11ALDH1A1PKMKDM4E | |
| SCHEMBL18586254 | 0.84 | KIF11 (0.44) | KIF11ALDH1A1PKMKDM4EHPGD | |
| SCHEMBL19639118 | 0.84 | TSHR (0.50) | CYP3A4MAPTRAB9ANPC1CYP1A2 | |
| SCHEMBL12493701 | 0.82 | PTGDR2 (0.50) | CYP3A4MAPTRAB9ANPC1KIF11 | |
| SCHEMBL3792211 | 0.81 | KIF11 (0.52) | MAPTRAB9ANPC1NPBWR1KIF11 | |
| SCHEMBL16193476 | 0.81 | L3MBTL1 (0.59) | MAPTRAB9ASMN1; SMN2KDM4ECFTR | |
| SCHEMBL25011713 | 0.80 | NPBWR1 (0.45) | CYP3A4MAPTRAB9ANPC1CYP1A2 | |
| SCHEMBL10078969 | 0.79 | NPBWR1 (0.47) | CYP3A4MAPTRAB9ANPC1CYP1A2 | |
| SCHEMBL10713204 | 0.78 | TDP1 (0.54) | CYP3A4MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL1241668 | 0.78 | L3MBTL1 (0.41) | MAPTRAB9AKIF11CFTRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090105316-A1 | Biphenyl Thiazole Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | disclosed |
| US-20090105316-A1 | Biphenyl Thiazole Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | disclosed |
| US-20090105316-A1 | Biphenyl Thiazole Carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-04-23 | — | — | US | disclosed |
| EP-1786795-A2 | BIPHENYL THIAZOLE CARBOXAMIDES | Bayer CropScience AG (DE) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006024389-A2 | BIPHENYL THIAZOLE CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2006-03-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105316-A1 | Biphenyl Thiazole Carboxamides | MRPL21, CBR3, BRD4 | CYP3A4 56/4885MAPT 2171/4885RAB9A 3583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.