Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4158666 | 0.91 | TP53 (0.60) | TP53ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL14229016 | 0.88 | TP53 (0.68) | TP53ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL4055701 | 0.85 | CYP3A4 (0.58) | TP53ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL4157179 | 0.84 | TP53 (0.63) | TP53ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL4163295 | 0.79 | TP53 (0.83) | TP53ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL4150527 | 0.78 | ALDH1A1 (0.59) | TP53ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL28385058 | 0.77 | MEN1 (0.48) | TP53ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL4160257 | 0.76 | LMNA (0.44) | TP53ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL4163289 | 0.76 | TSHR (0.52) | TP53ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL4058268 | 0.76 | POLB (0.59) | TP53ALDH1A1MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | LABORATORIOS SALVAT, S.A. (ES) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | PPARG, PPARD, TYRO3 | TP53 1939/4885ALDH1A1 2505/4885MEN1 4879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.