Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 7/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4159149 | 0.87 | ALDH1A1 (0.52) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL4159631 | 0.87 | HDAC4 (0.47) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL4165005 | 0.86 | ALDH1A1 (0.41) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL4174395 | 0.86 | ALDH1A1 (0.48) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL4162559 | 0.84 | ALDH1A1 (0.41) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL4160412 | 0.82 | HTT (0.46) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL4168844 | 0.82 | PLOD2 (0.46) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL3507991 | 0.82 | ALDH1A1 (0.45) | HDAC4HDAC1HDAC3HDAC7HDAC2 | |
| SCHEMBL4164026 | 0.82 | ALDH1A1 (0.54) | HDAC4ALDH1A1TSHRMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4157968 | 0.79 | PADI4 (0.49) | HDAC4HDAC1HDAC3HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | HDAC4 4/4885HDAC1 2/4885HDAC3 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.