Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI4 | Q9UM07 | 8/20 | 0.49 |
| ▸ | PADI1 | Q9ULC6 | 7/20 | 0.49 |
| ▸ | PADI2 | Q9Y2J8 | 5/20 | 0.49 |
| ▸ | PADI3 | Q9ULW8 | 5/20 | 0.48 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.44 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.44 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168844 | 0.97 | PLOD2 (0.46) | PADI4PADI1PADI2PADI3PLOD2 | |
| Trifluoroacetic Acid SCHEMBL4157970 | 0.83 | PLOD2 (0.44) | PLOD2PLOD3PLOD1LMNAECE1 | |
| SCHEMBL4174326 | 0.82 | KMT2A (0.52) | LMNAECE1HDAC3HDAC4HDAC1 | |
| SCHEMBL4159834 | 0.81 | EPHX2 (0.43) | PLOD2PLOD3PLOD1LMNAHDAC3 | |
| SCHEMBL4169482 | 0.81 | ALDH1A1 (0.45) | PLOD2PLOD3PLOD1HDAC3HDAC4 | |
| SCHEMBL4159631 | 0.80 | HDAC4 (0.47) | PLOD2PLOD3PLOD1LMNAHDAC3 | |
| SCHEMBL4158976 | 0.79 | HDAC4 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4168853 | 0.79 | PLOD2 (0.46) | PLOD2PLOD3PLOD1LMNAHDAC1 | |
| SCHEMBL4166897 | 0.79 | PADI4 (0.41) | PADI4PADI1PADI2PADI3PDE4A | |
| SCHEMBL4159149 | 0.79 | ALDH1A1 (0.52) | LMNAHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | JONES PHILIP | 2009-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054448-A1 | Amino Acid Derivatives as Histone Deacetylase (HDAC) Inhibitors | HDAC5, HDAC1, HDAC11 | PADI4 374/4885PADI1 314/4885PADI2 495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.